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Table 1 Characteristics and non-participation levels of included studies

From: Non-participation in population-based disease prevention programs in general practice

First author and year

Study design

Study size (n)

Country

Target disease

Inclusion criteria target group

Recruitment strategy

Non-participation level

Study quality#

Vaccination

        

Allsup [21], 2002

RCT

2583

UK

Influenza

Age (65–74), medical record

Letter + reminder

88% *

**

Arthur [22], 2002

RCT

2052

UK

Influenza

Age (≥ 75)

Letter

health check + vaccination: 26% vaccination in clinic: 32%

*

Evans [24], 2003

Observational

2600

UK

Influenza

Age (≥ 65)

Not clear

na

*

MRC Trial of Assessment and Management of Older People in the Community (MRC Study) Breeze [18], 2004 Mangtani [17], 2005 (sub study)

Observational

28492 5572

UK

Influenza

Age (≥ 75)

Letter

1997: 52% 1998: 50% 1999: 49% 2000: 37%

*

Byrnes [23], 2006

Observational

580

Australia

Influenza

Age (≥ 65)

Telephone + reminder

2004: 23% 2005: 17%

*

Opstelten [25], 2009

Observational

1778

The Netherlands

Herpes zoster and influenza

Age (≥ 65)

Letter + reminder

HZ (with and without influenza): 61%, Influenza (with and without HZ): 24%

*

Vila-Córcoles [26], 2006

Observational

10410

Spain

Pneumococcal bacteraemia/invasive disease

Age (≥ 65)

Not clear

2001: 56% 2002: 49% 2003: 48%

*

Screening aimed at early detection of disease

        

Moser [27], 2009

Observational

3185

UK

Cervical cancer

Age (25–64), female sex

Letter

na

*

Tacken [28], 2007

Observational

2224

The Netherlands

Cervical cancer

Age (30–60), female sex

Letter + reminder

na

*

Low [12], 2005

Observational

19773

UK

Chlamydia

Age (16–39)

Letter + reminder

65%

**

Verhoeven [29], 2004

Observational

339

Belgium

Chlamydia

Age (18–35), female sex

In General Practice practice

15%

*

Pilot ADDITION trial UK: Park [13, 14], 2008, 2010

RCT

355

UK

Diabetes

Age (40–69), medical record

Letter

18%

*

ADDITION trial UK: Sargeant [20], 2010 Eborall [16], 2007 (sub study)

Observational study Controlled trial

33539 7380

UK

Diabetes

Age (40–69), medical record

Letter + reminder

26%

*

ADDITION trial Denmark: Christensen [19], 2004 Dalsgaard [15], 2009 (sub study)

Observational

60926 4603

Denmark

Diabetes

Age (40–69), medical record

Letter

50%

*

Marteau [9], 2010

RCT

1272

UK

Diabetes

Age (40–69), medical record

Letter

43%

*

Van der Veen [30], 2009

Observational

8475

The Netherlands

Depression and anxiety

Age (18–65), recent contact PCP, medical record

Letter

64%

*

Yeung [31], 2006

Observational

5203

USA

Depression

Age (≥ 18), ethnicity

In General Practice practice

27%

*

Fowler [32], 2012

Observational

554

USA

Dementia

Age (≥ 65), medical record

In General Practice practice

10%

*

Screening aimed at identification of high risk of disease

        

Vermunt [36], 2010

Observational

16032

The Netherlands

Diabetes

Age (40–70), medical record

Letter

45%

**

Van de Kerkhof [33], 2010

Observational

1704

The Netherlands

Cardio-metabolic risk

Age (40–75), medical record

Letter

25%

*

Nielen [35], 2011

Observational

9896 **

The Netherlands

Cardio-metabolic risk

Age (45–70), medical record

Letter or poster and leaflets in waiting room

Letter: 67% Poster/leaflet: 99%

**

Lambert [34], 2011

Observational

24166

UK

Cardio-metabolic risk

Age (≥ 40), male sex, medical record

Letter or telephone call

76%

*

Barr [37], 2005

Observational

5306

UK

Fractures

Age (≥ 70), female sex

Letter

32%

*

Zanjani [38], 2006

Observational

8367

USA

Risk drinking

Age (≥ 65)

Not clear

52%

*

  1. na : not applicable.
  2. * : low participation level mainly due to the research design; randomized controlled trial of vaccination versus placebo.
  3. HZ: Herpes Zoster.
  4. **: in one half of the practices, GPs invited their selected patients by mail (n = 1583) and in the other half of the practices patients were invited by posters and leaflets in the waiting room (n = 8313 patients belonging to the target group).
  5. #: study quality. * = characteristics or reasons of non-participants given, ** = characteristics and reasons of non-participants given.