Table 5 Evaluation of the independent contribution of retained baseline variables for each prognostic score in NSCLC patients without surgery
From: Quality of life predicts survival in patients with non-small cell lung cancer
Variables | Non-surgery HR (95%C.I.) | |||
|---|---|---|---|---|
Model 1 | Model 2 | Model 3 | Model 4 | |
Gender (=Male as reference) | ||||
Female | 0.53 (0.36-0.79)** | 0.57 (0.38-0.85)** | 0.52 (0.35-0.78)** | 0.55 (0.37-0.82)** |
Age (yrs) (<50 as reference) | ||||
50 ≤ Age < 60 | 1.92 (1.08-3.39)* | 2.02 (1.15-3.56)* | 2.46 (1.38-4.36)** | 2.31 (1.3-4.11)** |
60 ≤ Age < 70 | 1.45 (0.86-2.44) | 1.47 (0.88-2.47) | 1.40 (0.82-2.39) | 1.41 (0.84-2.37) |
70 ≤ Age < 80 | 1.80 (1.07-3.03)* | 1.91 (1.13-3.24)* | 1.93 (1.12-3.32)* | 1.94 (1.15-3.29)* |
≥80 | 3.70 (1.73-7.89)*** | 4.53 (2.10-9.75)*** | 4.65 (2.14-10.08)*** | 4.73 (2.19-10.24)*** |
Cancer duration (yrs) (≥1 as reference) | ||||
New case | 1.19 (0.69-2.05) | 1.05 (0.61-1.82) | 1.28 (0.74-2.22) | 1.16 (0.66-2.01) |
Cancer duration <1 | 1.79 (1.08-2.97)* | 1.70 (1.02-2.82)* | 1.62 (0.97-2.69) | 1.62 (0.97-2.69) |
Type of Cancer (Adenocarcinoma as reference) | ||||
Squamous Cell | 0.91 (0.62-1.34) | 0.93 (0.62-1.37) | 0.87 (0.59-1.30) | 0.92 (0.62-1.37) |
Other | 1.20 (0.65-2.20) | 1.42 (0.75-2.68) | 1.23 (0.63-2.38) | 1.23 (0.64-2.36) |
Primary Tumor (T1 as reference) | ||||
T2 | 0.57 (0.28-1.16) | 0.60 (0.3-1.21) | 0.54 (0.27-1.08) | 0.54 (0.27-1.1) |
T3 | 1.20 (0.55-2.64) | 1.20 (0.54-2.65) | 1.19 (0.54-2.64) | 1.17 (0.53-2.58) |
T4 | 1.28 (0.67-2.46) | 1.32 (0.68-2.55) | 1.15 (0.59-2.23) | 1.22 (0.63-2.35) |
Regional Lymph Nodes (N0 as reference) | ||||
N1 | 1.06 (0.45-2.49) | 0.99 (0.42-2.31) | 1.12 (0.47-2.66) | 1.01 (0.43-2.37) |
N2 | 2.12 (1.24-3.61)** | 1.99 (1.17-3.38)* | 1.82 (1.05-3.14)* | 1.87 (1.09-3.20)* |
N3 | 2.29 (1.34-3.92)** | 2.14 (1.26-3.65)** | 1.85 (1.06-3.22)* | 1.84 (1.06-3.18)* |
Distant Metastasis (M0 as reference) | ||||
M1 | 1.54 (1.04-2.28)* | 1.52 (1.03-2.25)* | 1.37 (0.91-2.07) | 1.47 (0.99-2.19) |
QLQ-C30 | ||||
Social Functioning (<100 as reference) | ||||
=100 | 0.70 (0.50-0.99)* | 0.73 (0.52-1.03) | ||
Fatigue (≤11.12 as reference) | ||||
11.12 < FAS≤33.34 | 1.19 (0.77-1.86) | |||
>33.34 | 1.45 (0.92-2.28) | |||
Appetite Loss (=0 as reference) | ||||
>0 | 1.62 (1.12-2.36)* | 1.77 (1.26-2.49)** | ||
Financial Difficulties (=0 as reference) | ||||
>0 | 1.43 (0.99-2.06) | |||
−2 log likelihood | 1508.53 | 1490.90 | 1475.39 | 1480.24 |