Table 4 Evaluation of the independent contribution of retained baseline variables for each prognostic score in NSCLC patients with surgery
From: Quality of life predicts survival in patients with non-small cell lung cancer
Variables | Surgery HR (95%C.I.) | |||
|---|---|---|---|---|
Model 1 | Model 2 | Model 3 | Model 4 | |
Gender (=Male as reference) | ||||
Female | 0.90 (0.31-2.66) | 1.27 (0.41-3.89) | 1.62 (0.56-4.68) | 1.86 (0.63-5.56) |
Age (yrs) (<50 as reference) | ||||
50 ≤ Age < 60 | 1.54 (0.27-8.91) | 1.51 (0.26-8.93) | 2.24 (0.37-13.52) | 2.55 (0.43-15.11) |
60 ≤ Age < 70 | 3.71 (0.65-21.23) | 3.01 (0.48-19.06) | 3.88 (0.73-20.71) | 3.50 (0.60-20.30) |
70 ≤ Age < 80 | 3.32 (0.57-19.31) | 2.84 (0.46-17.65) | 3.53 (0.59-20.98) | 3.68 (0.63-21.63) |
≥80 | 41.03 (4.84-347.54)*** | 55.83 (5.76-541.35)*** | 168.87 (13.26-2150.64)*** | 283.27 (21.01-3819.27)*** |
Cancer duration (yrs) (≥1 as reference) | ||||
New case | 2.12 (0.65-6.92) | 2.13 (0.64-7.03) | 2.67 (0.70-10.12) | 3.34 (0.88-12.63) |
Cancer duration <1 | 2.24 (0.60-8.40) | 2.16 (0.55-8.49) | 3.71 (0.84-16.41) | 4.78 (1.05-21.74)* |
Type of Cancer (Adenocarcinoma as reference) | ||||
Squamous Cell | 1.76 (0.66-4.68) | 2.39 (0.86-6.7) | 2.57 (0.94-7.02) | 3.62 (1.21-10.86)* |
Other | 5.09 (1.03-25.12)* | 6.01 (1.00-35.92)* | 8.25 (1.58-43.09)* | 6.64 (1.12-39.39)* |
Primary Tumor (T1 as reference) | ||||
T2 | 0.84 (0.28-2.50) | 1.02 (0.33-3.20) | 1.33 (0.43-4.17) | 1.47 (0.45-4.81) |
T3 | 0.94 (0.23-3.78) | 1.17 (0.29-4.80) | 1.38 (0.35-5.48) | 1.63 (0.40-6.64) |
T4 | 1.54 (0.35-6.79) | 2.55 (0.52-12.56) | 4.42 (0.92-21.22) | 5.40 (0.99-29.51) |
Regional Lymph Nodes (N0 as reference) | ||||
N1 | 2.34 (0.85-6.45) | 2.98 (1.02-8.68)* | 2.73 (1.01-7.42)* | 3.80 (1.34-10.80)* |
N2 | 5.32 (1.70-16.64)** | 6.17 (1.88-20.19)** | 5.65 (1.68-18.96)** | 7.39 (2.15-25.43)** |
N3 | 6.74 (0.51-89.64) | 16.60 (0.98-282.16) | 4.55 (0.32-65.68) | 9.75 (0.62-153.58) |
Distant Metastasis (M0 as reference) | ||||
M1 | 1.73 (0.27-11) | 1.07 (0.16-7.39) | 1.51 (0.23-9.80) | 1.79 (0.29-11.21) |
QLQ-C30 | ||||
Emotional Functioning (<83.33 as reference) | ||||
83.33≤EFS < 100 | 3.36 (1.05-10.69)* | 2.56 (0.82-7.96) | ||
=100 | 2.00 (0.67-5.96) | 1.17 (0.39-3.56) | ||
Pain (=0 as reference) | ||||
0 < Pain≤22.22 | 0.24 (0.06-1.01) | |||
>22.22 | 0.83 (0.30-2.25) | |||
Nausea/Vomiting (=0 as reference) | ||||
>0 | 0.12 (0.02-0.71)* | 0.11 (0.02-0.63)* | ||
−2 log likelihood | 242.88 | 238.26 | 228.77 | 230.68 |