Table 3 Univariate and multivariate Cox’s analyses of baseline EORTC QLQ-LC13 for overall survival stratified by surgery status
From: Quality of life predicts survival in patients with non-small cell lung cancer
Variables | Surgery (N = 162) | Non-surgery (N = 312) | ||||||
|---|---|---|---|---|---|---|---|---|
N | # of death | Crude HR (95%C.I.) | Adjusted HR (95%C.I.) | N | # of death | Crude HR (95%C.I.) | Adjusted HR (95%C.I.) | |
QLQ-LC13 | ||||||||
Dyspnoea (=0 as reference) | 82 | 8 | 1.00 | 1.00 | 107 | 44 | 1.00 | 1.00 |
>0 | 79 | 26 | 2.03 (0.91-4.51) | 1.46 (0.51-4.16) | 201 | 120 | 1.32 (0.93-1.86) | 1.16 (0.80-1.69) |
Cough (=0 as reference) | 52 | 10 | 1.00 | 1.00 | 82 | 43 | 1.00 | 1.00 |
>0 | 109 | 24 | 1.31 (0.63-2.75) | 0.80 (0.33-1.91) | 230 | 125 | 1.19 (0.84-1.69) | 0.97 (0.68-1.40) |
Hemoptysis (=0 as reference) | 146 | 30 | 1.00 | 1.00 | 261 | 142 | 1.00 | 1.00 |
>0 | 15 | 4 | 2.23 (0.78-6.37) | 3.01 (0.81-11.18) | 50 | 26 | 1.57 (1.03-2.39)* | 1.04 (0.65-1.69) |
Sore Mouth (=0 as reference) | 154 | 30 | 1.00 | 1.00 | 278 | 147 | 1.00 | 1.00 |
>0 | 7 | 4 | 3.59 (1.26-10.20)* | 0.87 (0.14-5.48) | 33 | 21 | 1.16 (0.73-1.84) | 1.03 (0.60-1.76) |
Dysphagia (=0 as reference) | 144 | 29 | 1.00 | 1.00 | 257 | 135 | 1.00 | 1.00 |
>0 | 17 | 5 | 1.31 (0.51-3.40) | 0.58 (0.15-2.27) | 53 | 32 | 1.73 (1.18-2.55)** | 1.06 (0.68-1.64) |
Peripheral Neuropathy (=0 as reference) | 108 | 23 | 1.00 | 1.00 | 213 | 109 | 1.00 | 1.00 |
>0 | 53 | 11 | 0.86 (0.42-1.77) | 1.03 (0.41-2.59) | 97 | 59 | 1.10 (0.80-1.51) | 1.03 (0.73-1.46) |
Hair Loss (=0 as reference) | 140 | 29 | 1.00 | 1.00 | 262 | 137 | 1.00 | 1.00 |
>0 | 21 | 5 | 1.01 (0.39-2.62) | 0.32 (0.07-1.44) | 47 | 29 | 0.99 (0.66-1.47) | 1.11 (0.71-1.73) |
Chest Pain (=0 as reference) | 107 | 20 | 1.00 | 1.00 | 183 | 94 | 1.00 | 1.00 |
>0 | 54 | 14 | 1.05 (0.53-2.09) | 0.52 (0.21-1.32) | 128 | 73 | 1.07 (0.79-1.45) | 0.97 (0.70-1.34) |
Pain in Arm or Shoulder (=0 as reference) | 123 | 25 | 1.00 | 1.00 | 217 | 114 | 1.00 | 1.00 |
>0 | 37 | 9 | 0.86 (0.40-1.84) | 1.19 (0.45-3.14) | 93 | 53 | 1.20 (0.87-1.67) | 0.96 (0.66-1.39) |
Other Pain Sites (=0 as reference) | 117 | 26 | 1.00 | 193 | 106 | 1.00 | 1.00 | |
>0 | 41 | 7 | 0.60 (0.26-1.39) | 0.38 (0.12-1.19) | 106 | 53 | 1.02 (0.74-1.42) | 0.96 (0.67-1.38) |