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Table 4 Postoperative in-hospital mortality in 22289 incident colorectal cancer patients after curative surgery

From: Hospital factors and patient characteristics in the treatment of colorectal cancer: a population based study

  Total (N = 22289) Unadjusted mortality Random-effect model*
  No. % OR 95% CI P
Age (years)      
 ≤60 3,910 1.0 1   
 61-70 6,224 1.9 1.76 (1.20-2.57) <0.001
 71-80 8,124 4.0 2.30 (1.61-3.28)  
 >80 4,031 8.9 3.34 (2.33-4.79)  
Gender      
 Male 12,309 4.0 1   0.36
 Female 9,980 3.5 0.71 (0.60-0.84)  
Educational level      
 Secondary or more 3,165 1.2 1   <0.001
 Intermediate 4,745 2.6 1.14 (0.82-1.58)  
 Primary 11,625 4.4 1.25 (0.95-1.67)  
 Unknown 2,754 5.2 1.60 (1.10-2.32)  
Marital status      
 Married 14,221 3.1 1   <0.001
 Unmarried 6,212 5.0 1.32 (1.09-1.59)  
 Unknown 1,856 5.5 1.65 (1.20-2.29)  
OPE      
 No 14,558 1.8 1   <0.001
 Yes 7,731 7.5 1.54 (1.29-1.85)  
Disease staging      
 Absence of metastases 19,064 3.5 -   <0.001
 Presence of metastases 3,225 5.7 -   
Comorbidity (Charlson index)      
 0 16,145 3.2 -   <0.001
 ≥1 6,144 5.4 -   
Year of admission      
 2000 2,458 4.1 1   0.55
 2001 2,583 3.4 0.82 (0.59-1.14)  
 2002 2,651 4.1 0.95 (0.69-1.29)  
 2003 2,687 3.9 0.75 (0.55-1.03)  
 2004 2,924 4.4 0.77 (0.57-1.05)  
 2005 2,930 3.3 0.53 (0.38-0.73)  
 2006 3,006 3.5 0.54 (0.39-0.74)  
 2007 3,050 3.6 0.49 (0.34-0.68)  
Tumor site      
 Colon 15,256 4.1 1   <0.001
 Rectum 7,033 3.1 1.05 (0.87-1.27)  
Hospital volume (annual caseload)      
 >60 9,371 3.5 1   0.10
 26-60 9,430 3.9 0.87 (0.64-1.19)  
 <25 3,488 4.3 1.14 (0.76-1.69)  
APR-DRG risk-of-mortality score      
 Low 12,740 0.8 1   <0.001
 Medium 7,869 3.9 4.47 (3.54-5.66)  
 High 1,359 19.1 25.77 (19.80-33.54)  
 Extreme 321 56.7 153.03 (109.81-213.27)  
  1. *Given the correlation between APR-DRG risk-of-mortality score, tumor stage and comorbidity score these predictors were not included in the models simultaneously.
  2. ‡Unmarried includes single, separated, divorced and widowed.
  3. OR: odds ratio; CI: confidence interval; APR-DRG: all-patient-refined-diagnosis-related group; OPE: obstruction, perforation or emergency admission.