From: Implementing new health interventions in developing countries: why do we lose a decade or more?
 | Relevance to access | Considerations |
---|---|---|
Prior to regulatory approval | Availability & Affordability | Design of interventions specifically for the needs of DCs [31–37] |
Adoption | Clinical studies to address questions unique to DCs [12, 38–42] | |
 | Requirements for international policy recommendations [43, 44] | |
 | Preparing for country decision-making processes [45] | |
After regulatory approval | Coordinated action | Coordination between stakeholders [16] |
Availability | Alignment of intervention with the unique needs of developing country health systems [16, 18, 19, 23, 24] | |
 | Forecasting and manufacturing plans incorporating DCs, [16, 21] | |
 | ||
Affordability | Affordability, financing, & cost-effectiveness [16, 18, 19, 21–24, 27–30] | |
Adoption | Research aligned with policy-maker needs, including burden of disease addressed by an intervention [18, 21–24, 29] | |
 | Importance of international technical consensus and recommendations, including influence of neighboring countries [21, 23, 46] | |
 | Strengthened national processes, acceptability, and/or governance [17, 19–21, 26] |