| Control arm n = 5304 | Screening arm n = 5305 | P-value* | Screening attendees | Screening non-attendees | Univariate OR (95% CI)†| Multivariate OR (95% CI)†|
---|---|---|---|---|---|---|---|
Age at randomization, mean (range), yrs | 56.7 (39.9 – 75.9) | 56.6 (39.9 – 76.0) | 0.299 | 57.0 | 54.4 | 1.03 (1.02-1.04), p < 0.001 | 1.03 (1.02 – 1.04), p < 0.001 |
Gender, male, % | 43.9 | 43.7 | 0.778 | 43.4 | 44.9 | 0.94 (0.81-1.09), p = 0.422 |  |
Marital status, married, % | 74.4 | 73.6 | 0.379 | 75.4 | 64.5 | 1.69 (1.44-1.97), p < 0.001 | 1.57 (1.33 – 1.83), p < 0.001 |
Highest education completed, % | Â | Â | Â | Â | Â | Â | Â |
Primary | 9.5 | 9.6 | 0.917 | 9.2 | 11.2 | 0.89 (0.68-1.16), p = 0.400 |  |
Lower secondary | 40.8 | 39.9 |  | 40.3 | 38.2 | 1.14 (0.95-1.37), p = 0.169 |  |
Upper secondary | 24.2 | 24.8 |  | 25.3 | 23.1 | 1.18 (0.96-1.45), p = 0.126 |  |
Tertiary | 24.4 | 24.6 | Â | 24.3 | 26.3 | Reference | Â |
Smoking status, current smoker, % | 18.7 | 19.8 | 0.389 | 17.6 | 31.1 | 0.47 (0.40-0.56), p < 0.001 | 0.52 (0.44 – 0.62), p < 0.001 |
Waist circumference, mean, cm | 96.2 | 96.6 | 0.214 | 96.6 | 96.6 | 1.00 (0.99-1.01), p = 0.377 |  |
  Females 80–87, % | 25.3 | 25.3 | 0.266 | 24.6 | 28.7 |  |  |
     > = 88, % | 74.7 | 74.7 |  | 75.4 | 71.3 |  |  |
  Males 94–101, % | 46.4 | 46.5 | 0.282 | 47.2 | 43.0 |  |  |
     > = 102, % | 53.5 | 53.5 |  | 52.6 | 57.0 |  |  |
Diabetes family history, % | 27.2 | 26.4 | 0.350 | 26.5 | 25.8 | 1.04 (0.88-1.23), p = 0.674 |  |
Country of birth, % | Â | Â | Â | Â | Â | Â | Â |
Netherlands | 91.4 | 91.1 | 0.583 | 91.5 | 88.9 | 1.34 (1.05-1.70), p = 0.017 | 1.20 (0.94-1.54), p = 0.138 |
Other | 8.6 | 8.9 | Â | 8.5 | 11.1 | Â | Â |
  Western country‡ | 4.0 | 4.0 |  | 4.1 | 3.5 |  |  |
  Non-western country | 4.6 | 4.9 |  | 4.4 | 7.5 |  |  |
Screening outcome | Â | Â | Â | Â | Â | Â | Â |
Attendance rate, n, (%) | – | 4457 (84.0) |  |  |  |  |  |
Impaired fasting glucose, n (%) | – | 170 (3.8) |  |  |  |  |  |
Diabetes, n (%) | – | 81 (1.8) |  |  |  |  |  |
SCORE† > =5%, | – | 518 (11.6) |  |  |  |  |  |