Table 4 Dose response measurement of liver function test parameters and autoimmune markers with urinary arsenic concentration
|  | Group A (N = 15) | Group B (N = 40) | Group C (N = 24) | Group D (N = 24) | P –Values for dose response effects |
|---|---|---|---|---|---|
Bilirubin (mg/dl) | 0.63 ± 0.28 | 0.68 ± 0.23 | 0.71 ± 0.33 | 0.69 ± 0.21 | 0.872 |
AST (U/L) | 48.70 ±16.35 | 51.65 ± 8.47 | 57.86 ± 10.61 | 51.92 ± 8.43 | 0.039* |
ALT (U/L) | 30.87 ± 7.87 | 37.95 ± 9.26 | 40.58 ± 9.91 | 41.38 ± 12.88 | 0.013* |
Total Protein (g/dl) | 8.18 ± 0.77 | 8.19 ± 0.78 | 8.44 ± 0.85 | 8.41 ± 0.72 | 0.564 |
ALP (U/L) | 216.87 ± 86.49 | 221.41 ± 50.74 | 215.25 ± 133.65 | 241.67 ± 67.27 | 0.098 |
GGTP (U/L) | 11.67 ± 2.16 | 13.27 ± 6.65 | 14.25 ± 9.08 | 16.91 ± 11.12 | 0.172 |
ANA | 0.85 ± 0.34 | 1.24 ± 1.10 | 1.18 ± 0.62 | 1.35 ± 0.63 | 0.025** |
Anti ds DNA | 0.65 ± 0.33 | 0.77 ± 0.50 | 0.53 ± 0.37 | 0.88 ± 0.60 | 0.017** |