Table 2 Univariate regression analysis (95% CI) of lipid and glucose metabolism with potential mediators
Cholesterol | HDL-C | LDL-C | Log(triglycerides) | Glucose | Log(C-peptide) | Insulin resistance | |
|---|---|---|---|---|---|---|---|
Age | 0.09 (0.00 – 0.18) ** | 0.10 (0.06 – 0.13) **** | 0.14 (0.06 – 0.22) | 0.01 (−0.01 – 0.04) | 0.14 (0.08 – 0.21) **** | −0.10 (−0.12 - -0.09) **** | −0.15 (−0.19 - - 0.10) **** |
Sex (reference: boys) | 0.19 (0.12 – 0.26) **** | −0.02 (−0.05 – 0.01) | 0.24 (0.17 – 0.30) **** | 0.06 (0.04 – 0.08) **** | −0.13 (−0.18 - -0.08) **** | 0.02 (0.01 – 0.03) *** | 0.01 (−0.02 – 0.05) |
Height in meters | −0.33 (−0.99 – 0.33) * | 0.15 (−0.15 – 0.45) | −0.03 (−0.66 – 0.60) | −0.01 (−0.19 – 0.18) | 1.20 (0.73 – 1.68) **** | −0.13 (−0.25 – -0.00) ** | −0.07 (−0.37 – 0.22) |
Size at birth (reference: AGA) | |||||||
SGA | 0.06 (−0.11 – 0.22) | 0.08 (0.01 – 0.16) ** | −0.04 (−0.19 – 0.12) | 0.01 (−0.04 – 0.05) | −0.02 (−0.14 – 0.10) | −0.01 (−0.04 – 0.02) | 0.00 (−0.07 – 0.07) |
LGA | −0.12 (−0.22 - -0.01) ** | −0.04 (−0.09 – 0.01) | −0.10 (−0.20 – 0.00) * | −0.01 (−0.04 – 0.02) | 0.01 (−0.06 – 0.09) | 0.01 (−0.01 – 0.03) | 0.04 (0.00 – 0.09) * |
Maternal BMI | 0.00 (−0.01 – 0.01) | 0.00 (−0.01 – 0.00) | 0.01 (−0.00 – 0.02) * | 0.00 (−0.00 – 0.00) | 0.01 (−0.00 – 0.02) | 0.00 (−0.00 – 0.00) | 0.00 (−0.01 – 0.00) |
Breastfeeding duration (reference: > 3 months) | |||||||
< 1 month | −0.02 (−0.11 – 0.07) | −0.04 (−0.08 – 0.00) | 0.00 (−0.09 – 0.09) | 0.02 (−0.00 – 0.05) * | −0.01 (−0.08 – 0.06) | 0.00 (−0.01 – 0.02) | 0.00 (−0.04 – 0.04) |
1 – 3 months | 0.08 (−0.01 – 0.17) | 0.01 (−0.03 – 0.05) | 0.07 (−0.02 – 0.15) | 0.00 (−0.02 – 0.03) | 0.00 (−0.06 – 0.07) | 0.00 (−0.02 – 0.01) | 0.01 (−0.03 – 0.05) |
Childhood sdsBMI | 0.01 (−0.04 – 0.06) | −0.01 (−0.03 – 0.01) | 0.01 (−0.03 – 0.05) | 0.01 (−0.01 – 0.02) | 0.05 (0.02 – 0.08) *** | 0.03 (0.02 – 0.04) **** | 0.04 (0.02 – 0.06) **** |
Sports club member (reference: yes) | −0.01 (−0.09 – 0.07) | 0.01 (−0.03 – 0.04) | −0.02 (−0.09 – 0.05) | 0.00 (−0.02 – 0.02) | 0.05 (−0.01 – 0.10) * | −0.01 (−0.02 – 0.01) | 0.00 (−0.03 – 0.04) |
Walking to school (reference: > 60 min a week) | |||||||
No | 0.09 (−0.02 – 0.21) | −0.02 (−0.07 – 0.03) | 0.04 (−0.07 – 0.15) | 0.00 (−0.03 – 0.03) | 0.01 (−0.07 – 0.09) | 0.01 (−0.01 – 0.04) | 0.03 (−0.02 – 0.08) |
< 30 min a week | 0.07 (−0.06 – 0.19) | −0.01 (−0.07 – 0.05) | 0.05 (−0.07 – 0.17) | 0.00 (−0.04 – 0.03) | 0.00 (−0.09 – 0.09) | 0.01 (−0.02 – 0.03) | 0.01 (−0.05 – 0.06) |
31 – 60 min a week | 0.05 (−0.08 – 0.18) | −0.04 (−0.10 – 0.02) | 0.03 (−0.10 – 0.16) | 0.01 (−0.03 – 0.05) | 0.06 (−0.03 – 0.16) | 0.02 (−0.01 – 0.04) | 0.05 (−0.01 – 0.11) |
Cycling to school (reference: > 60 min a week) | |||||||
No | −0.04 (−0.17 – 0.09) | −0.05 (−0.10 – 0.01) | −0.07 (−0.19 – 0.05) | 0.01 (−0.03 – 0.04) | −0.01 (−0.10 – 0.09) | 0.00 (−0.02 – 0.03) | −0.02 (−0.07 – 0.04) |
< 30 min a week | −0.06 (−0.21 – 0.09) | −0.03 (−0.10 – 0.04) | −0.07 (−0.21 – 0.07) | −0.02 (−0.06 – 0.02) | 0.03 (−0.08 – 0.14) | 0.00 (−0.02 – 0.03) | −0.02 (−0.09 – 0.05) |
31 – 60 min a week | −0.06 (−0.22 – 0.10) | −0.01 (−0.08 – 0.07) | −0.08 (−0.23 – 0.08) | −0.01 (−0.06 – 0.03) | 0.02 (−0.10 – 0.14) | 0.01 (−0.02 – 0.05) | 0.00 (−0.07 – 0.08) |