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Table 3 Patient, condition and therapy-related factors of cases and controls with TB, stratified by patient category, South Africa, 2002

From: Patient- and provider-level risk factors associated with default from tuberculosis treatment, South Africa, 2002: a case-control study

  

New TB Patient (N = 926)

Re-treatment TB Patient (N = 236)

Combined

  

Cases (160)

Controls (766)

OR(95% CI)

Cases (71)

Controls (165)

OR (95% CI)

OR*(95% CI)

AOR† (95% CI)

Characteristic

n/N

%

n/N

%

 

n/N

%

n/N

%

   

Felt ashamed about TB

Yes

67/155

43

181/753

24

2.4 (1.6-3.5)

31/71

44

48/164

30

1.9 (1.0-3.5)

2.3 (1.7-3.1)

2.2 (1.6-3.0)

 

No

88/155

67

572/753

76

 

40/71

56

116/164

70

   

Felt supported by family

Yes

116/153

76

651/736

88

0.4 (0.2-0.6)

54/67

80

140/160

88

0.6 (0.3-1.4)

0.5 (0.3-0.7)

0.5 (0.3-0.7)

 

No

37/153

24

85/736

12

 

13/67

20

20/160

22

   

Knew treatment duration was ≥ 6 months

Yes

108/149

72

623/741

84

0.9 (0.4-2.0)

55/69

80

133/163

82

0.5 (0.3-0.8)

0.6 (0.4-0.8)

0.6 (0.4-0.8)

 

No

41/149

28

118/741

16

 

14/69

20

30/163

18

   

Felt they might die from TB

Yes

96/154

62

511/749

68

0.8 (0.5-1.1)

41/65

63

118/159

74

0.6 (0.3-1.2)

0.7 (0.5-1.0)

0.7 (0.5-1.0)

 

No

58/154

38

238/749

32

 

24/65

37

41/159

26

   

Thought they would finish taking treatment

Yes

112/143

78

573/734

78

1.0 (0.6-1.6)

52/63

63

130/152

74

0.8 (0.3-2.0)

1.0 (0.7-1.5)

1.0 (0.7-1.4)

 

No

31/143

22

161/734

22

 

11/63

17

22/152

    

Felt that it is possible to cure TB

Yes

119/123

97

729/738

99

0.4 (0.1-1.7)

58/62

94

149/153

97

0.4 (0.1-2.2)

0.3 (0.1-0.9)

0.4 (0.2-0.9)

 

No

4/123

3

9/738

1

 

4/62

6

5/153

3

   

Saw a traditional healer during TB treatment

Yes

30/159

19

52/757

7

3.2 (1.8-5.3)

9/69

13

12/165

7

1.9 (0.7-5.2)

2.8 (1.7-4.3)

2.8 (1.8-4.3)

 

No

129/159

18

705/757

93

 

60/69

87

153/165

93

   

Type of TB

Pulmonary

150/157

96

732/749

98

0.9 (0.2-1.4)

63/69

99

157/161

98

0.3 (0.05-1.2)

0.4 (0.2-0.9)

0.4 (0.2-0.8)

 

Extra Pulmonary

7/157

4

17/749

2

 

6/69

1

5/161

2

   

Alcohol use

Yes

51/154

33

157/753

21

1.9 (1.3-2.8)

27/70

39

46/163

28

1.6 (0.8-2.3)

1.9 (1.3-2.6)

1.8 (1.3-2.5)

 

No

103/154

77

596/753

79

 

43/70

61

117/163

72

   

Marijuana/mandrax use

Yes

6/159

4

29/756

4

1.0 (0.3-2.5)

8/71

11

9/165

5

2.2 (0.7-6.7)

1.5 (0.7-2.9)

1.4 (0.7-2.6)

 

No

153/159

96

727/756

96

 

63/71

89

156/165

95

   

History of default

No

n/a

n/a

n/a

n/a

n/a

26/165

16

38/71

53

6.2 (3.1-12)

n/a

n/a

 

Yes

n/a

n/a

n/a

n/a

n/a

139/165

84

33/71

47

   

Hospitalized for TB treatment

Yes

54/155

35

287/758

38

0.9 (0.6-1.1)

25/70

36

66/163

40

0.8 (0.4-1.5)

0.9 (0.6-1.2)

0.9 (0.6-1.2)

 

No

101/155

65

471/758

62

 

45/70

64

97/163

60

   

Felt better with treatment

No

32/150

21

15/754

2

13.3(7.0-27)

18/67

27

5/162

3

11.5 (3.9-41)

13.3 (7.5-24)

12.7 (7.3-22)

 

Yes

118/150

79

739/754

98

 

49/67

73

157/162

97

   

Treatment side effects

Yes

73/138

53

297/679

44

1.4 (1.0-2.2)

39/60

65

79/152

52

1.7 (0.9-7.8)

1.6 (1.2-2.2)

1.5 (1.1-2.1)

 

No

65/138

47

382/679

56

 

21/60

35

73/152

48

   

Spent ≥ 1 day without food during treatment

Yes

28/155

18

98/759

13

1.5 (0.9-2.4)

16/70

23

30/163

18

1.3 (0.6-2.7)

1.5 (1.0-2.2)

1.4 (0.9-2.1)

 

No

127/155

82

661/759

87

 

54/70

77

133/163

82

   

Took TB treatment on an empty stomach

Yes

49/142

35

183/725

25

1.6 (1.0-2.3)

24/62

39

43/160

27

1.7 (0.9-3.3)

1.6 (1.2-2.3)

1.6 (1.2-2.2)

 

No

93/142

65

542/729

75

 

38/62

61

117/160

73

   
  1. *Combined bivariate odds ratio
  2. † Odds ratio adjusted by patient category