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Table 3 Patient, condition and therapy-related factors of cases and controls with TB, stratified by patient category, South Africa, 2002

From: Patient- and provider-level risk factors associated with default from tuberculosis treatment, South Africa, 2002: a case-control study

   New TB Patient (N = 926) Re-treatment TB Patient (N = 236) Combined
   Cases (160) Controls (766) OR(95% CI) Cases (71) Controls (165) OR (95% CI) OR*(95% CI) AOR† (95% CI)
Characteristic n/N % n/N %   n/N % n/N %    
Felt ashamed about TB Yes 67/155 43 181/753 24 2.4 (1.6-3.5) 31/71 44 48/164 30 1.9 (1.0-3.5) 2.3 (1.7-3.1) 2.2 (1.6-3.0)
  No 88/155 67 572/753 76   40/71 56 116/164 70    
Felt supported by family Yes 116/153 76 651/736 88 0.4 (0.2-0.6) 54/67 80 140/160 88 0.6 (0.3-1.4) 0.5 (0.3-0.7) 0.5 (0.3-0.7)
  No 37/153 24 85/736 12   13/67 20 20/160 22    
Knew treatment duration was ≥ 6 months Yes 108/149 72 623/741 84 0.9 (0.4-2.0) 55/69 80 133/163 82 0.5 (0.3-0.8) 0.6 (0.4-0.8) 0.6 (0.4-0.8)
  No 41/149 28 118/741 16   14/69 20 30/163 18    
Felt they might die from TB Yes 96/154 62 511/749 68 0.8 (0.5-1.1) 41/65 63 118/159 74 0.6 (0.3-1.2) 0.7 (0.5-1.0) 0.7 (0.5-1.0)
  No 58/154 38 238/749 32   24/65 37 41/159 26    
Thought they would finish taking treatment Yes 112/143 78 573/734 78 1.0 (0.6-1.6) 52/63 63 130/152 74 0.8 (0.3-2.0) 1.0 (0.7-1.5) 1.0 (0.7-1.4)
  No 31/143 22 161/734 22   11/63 17 22/152     
Felt that it is possible to cure TB Yes 119/123 97 729/738 99 0.4 (0.1-1.7) 58/62 94 149/153 97 0.4 (0.1-2.2) 0.3 (0.1-0.9) 0.4 (0.2-0.9)
  No 4/123 3 9/738 1   4/62 6 5/153 3    
Saw a traditional healer during TB treatment Yes 30/159 19 52/757 7 3.2 (1.8-5.3) 9/69 13 12/165 7 1.9 (0.7-5.2) 2.8 (1.7-4.3) 2.8 (1.8-4.3)
  No 129/159 18 705/757 93   60/69 87 153/165 93    
Type of TB Pulmonary 150/157 96 732/749 98 0.9 (0.2-1.4) 63/69 99 157/161 98 0.3 (0.05-1.2) 0.4 (0.2-0.9) 0.4 (0.2-0.8)
  Extra Pulmonary 7/157 4 17/749 2   6/69 1 5/161 2    
Alcohol use Yes 51/154 33 157/753 21 1.9 (1.3-2.8) 27/70 39 46/163 28 1.6 (0.8-2.3) 1.9 (1.3-2.6) 1.8 (1.3-2.5)
  No 103/154 77 596/753 79   43/70 61 117/163 72    
Marijuana/mandrax use Yes 6/159 4 29/756 4 1.0 (0.3-2.5) 8/71 11 9/165 5 2.2 (0.7-6.7) 1.5 (0.7-2.9) 1.4 (0.7-2.6)
  No 153/159 96 727/756 96   63/71 89 156/165 95    
History of default No n/a n/a n/a n/a n/a 26/165 16 38/71 53 6.2 (3.1-12) n/a n/a
  Yes n/a n/a n/a n/a n/a 139/165 84 33/71 47    
Hospitalized for TB treatment Yes 54/155 35 287/758 38 0.9 (0.6-1.1) 25/70 36 66/163 40 0.8 (0.4-1.5) 0.9 (0.6-1.2) 0.9 (0.6-1.2)
  No 101/155 65 471/758 62   45/70 64 97/163 60    
Felt better with treatment No 32/150 21 15/754 2 13.3(7.0-27) 18/67 27 5/162 3 11.5 (3.9-41) 13.3 (7.5-24) 12.7 (7.3-22)
  Yes 118/150 79 739/754 98   49/67 73 157/162 97    
Treatment side effects Yes 73/138 53 297/679 44 1.4 (1.0-2.2) 39/60 65 79/152 52 1.7 (0.9-7.8) 1.6 (1.2-2.2) 1.5 (1.1-2.1)
  No 65/138 47 382/679 56   21/60 35 73/152 48    
Spent ≥ 1 day without food during treatment Yes 28/155 18 98/759 13 1.5 (0.9-2.4) 16/70 23 30/163 18 1.3 (0.6-2.7) 1.5 (1.0-2.2) 1.4 (0.9-2.1)
  No 127/155 82 661/759 87   54/70 77 133/163 82    
Took TB treatment on an empty stomach Yes 49/142 35 183/725 25 1.6 (1.0-2.3) 24/62 39 43/160 27 1.7 (0.9-3.3) 1.6 (1.2-2.3) 1.6 (1.2-2.2)
  No 93/142 65 542/729 75   38/62 61 117/160 73    
  1. *Combined bivariate odds ratio
  2. † Odds ratio adjusted by patient category