Co-morbid depression is associated with poor work outcomes in persons with cardiovascular disease (CVD): A large, nationally representative survey in the Australian population

Table 4 Logistic regression model for the relationship between impaired work functioning and disease group (employed participants) (n = 5499)

Amount of difficulty in day to day work⁺	Unadjusted	Adjusted	Jack-knife	95%
	Odds Ratio	Odds ratio±	Standard	Confidence
			Error	intervals
Condition
Neither CVD nor MDD	1.0
MDD only	4.3*	3.8*	0.4	3.0, 4.8
CVD only	1.0	0.9	0.2	0.6, 1.4
Co-morbid MDD & CVD	10.7*	8.1*	3.0	3.8, 17.3
CVD-MDD interaction		2.4*	1.0	1.01, 5.7

⁺ 0 = None or not known, 1 = Mild- Extreme difficulty, where 0 is the reference group; ± = Adjusted for age, sex, country of birth, education, smoking, chronic lifetime physical condition, number of hours worked per week; Goodness of fit [27] and link tests produced non-significant test statistics (p = 0.24 and p = 0.051 respectively), reflecting goodness of fit and sound model specificity

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