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Table 2 Seasonal influenza vaccination and H1N1 infection stratified by healthy users and social determinants

From: The potential effect of temporary immunity as a result of bias associated with healthy users and social determinants on observations of influenza vaccine effectiveness; could unmeasured confounding explain observed links between seasonal influenza vaccine and pandemic H1N1 infection?

Healthy User = 0 Social Determinant = 1   H1N1   Total  
    + -   
  Vaccinated + 12 28 40  
   - 48 112 160  
    60 140 200  
Healthy User = 1 Social Determinant = 1   H1N1   Total  
    + -   
  Vaccinated + 140 60 200  
   - 140 60 200  
    280 120 400  
Healthy User = 0 Social Determinant = 0   H1N1   Total  
    + -   
  Vaccinated + 64 96 160  
   - 96 144 240  
    160 240 400  
Summary Table
    H1N1   Total  
    + -   
  Vaccinated + 216 184 400 OR§ =1.3
   - 284 316 600 95% CI: 1.0 to 1.7
    500 500 1000 OR M-H = 1.0
       95% CI: 0.8 to 1.3