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Table 1 sample size calculations

From: ‘Decision support system (DSS) for prevention of cardiovascular disease (CVD) among hypertensive (HTN) patients in Andhra Pradesh, India’ – a cluster randomised community intervention trial

Detectable difference in SBP between both the groups

80% power with an ICC of 0.02

90% power with an ICC of 0.02

Sample size required for individual randomization per arm

Sample size required for cluster randomization per arm (DE = 2.98)

Sample size required for cluster randomization with CV = 0.25 (DE = 3.1)

Minimum no of clusters with a cluster size of 100

Sample size required for individual randomization per arm

Sample size required for cluster randomization per arm (DE = 2.98)

Sample size required for cluster randomization with CV = 0.25 (DE = 3.1)

Minimum no of clusters with a cluster size of 100

4 mm of Hg

374

1115

1160

24

500

1490

1550

32

5 mm of Hg

239

713

741

16

320

954

992

20

6 mm of Hg

166

495

515

12

222

622

689

14

  1. ICC = Intra Cluster correlation; DE = design effect; CV = coefficient of variation.