Figure 1

Design of the DH!AAN study. Legend: ^aFPG of 100–125 mg/dl (5.6–6.9 mmol/l) and/or 2-h postload glucose of 140–199 mg/dl (7.8–11.0 mmol/l), ^bHOMA-IR ≥ 2.39. ADA, American Diabetes Association; FPG, fasting plasma glucose; IFG, impaired fasting glucose; IGT, impaired glucose tolerance; Hb_A1c, glycated hemoglobin; HOMA-IR, homeostasis model assessment of estimated insulin resistance; M, measurements; RCT, randomized controlled trial.