Table 6 Association of various factors with chronic kidney disease (eGFR <60 mL/min/1.73 m 2 ) based on different estimating equations
MDRD GFR | CKD-Epi | CsyC-based CKD | |||||
|---|---|---|---|---|---|---|---|
crude | adjusteda | crude | adjusteda | crude | adjusteda | ||
Age | 65–69 | 1.00 (referent) | 1.00(referent) | 1.00(referent) | 1.00(referent) | 1.00(referent) | 1.00(referent) |
70–79 | 1.60 (1.18; 2.16) | 1.52 (1.11; 2.10) | 2.09 (1.49; 2.91) | 1.98 (1.40; 2.81) | 3.36 (1.75; 6.45) | 3.30 (1.64; 6.67) | |
≥80 | 3.57 (2.61; 4.89) | 3.33 (2.37; 4.74) | 6.41 (4.55; 9.03) | 6.01 (4.14; 8.73) | 13.66 (7.25; 25.73) | 13.94 (6.95; 27.98) | |
Gender | female | 1.47 (1.18; 1.83) | 1.63 (1.23; 2.16) | 1.15 (0.92; 1.43) | 1.23 (0.92; 1.65) | 1.04 (0.77; 1.39) | 0.89 (0.58; 1.34) |
Family status | Married | 1.00(referent) | 1.00(referent) | 1.00(referent) | 1.00(referent) | 1.00(referent) | 1.00(referent) |
widowed | 1.94 (1.51; 2.49) | 1.24 (0.93; 1.65) | 2.09 (1.63; 2.69) | 1.29 (0.96; 1.74) | 2.11 (1.54; 2.90) | 1.17 (0.79; 1.74) | |
other | 1.29 (0.89; 1.86) | 1.12 (0.75; 1.67) | 1.40 (0.97; 2.03) | 1.33 (0.88; 2.00) | 1.29 (0.78; 2.14) | 1.34 (0.75; 2.38) | |
Duration of | ≤9 yrs | 1.00(referent) | 1.00(referent) | 1.00(referent) | 1.00(referent) | 1.00(referent) | 1.00(referent) |
school education | 10–11 yrs | 1.01 (0.77; 1.31) | 1.11 (0.83; 1.47) | 1.00 (0.76; 1.31) | 1.13 (0.84; 1.52) | 1.02 (0.72; 1.46) | 1.17 (0.78; 1.75) |
≥12 yrs | 0.96 (0.72; 1.29) | 1.18 (0.86; 1.63) | 0.93 (0.69; 1.25) | 1.11 (0.80; 1.54) | 0.72 (0.47; 1.10) | 0.85 (0.53; 1.37) | |
Alcohol consumption | daily | 0.49 (0.36; 0.68) | 0.69 (0.48; 1.01) | 0.54 (0.39; 0.75) | 0.66 (0.45; 0.97) | 0.43 (0.29; 0.64) | 0.40 (0.24; 0.66) |
several time per week or per month | 0.54 (0.40; 0.72) | 0.72 (0.52; 1.00) | 0.55 (0.41; 0.74) | 0.70 (0.50; 0.98) | 0.37 (0.26; 0.54) | 0.39 (0.25; 0.60) | |
<1 time per month | 1.00(referent) | 1.00(referent) | 1.00(referent) | 1.00(referent) | 1.00(referent) | 1.00(referent) | |
never | 0.81 (0.25; 2.62) | 0.57 (0.17; 1.95) | 1.25 (0.39; 3.99) | 0.93 (0.28; 3.14) | 0.97 (0.26; 3.71) | 0.68 (0.16; 2.91) | |
Smoking status | smoker | 0.56 (0.37; 0.86) | 0.73 (0.46; 1.16) | 0.61 (0.40; 0.94) | 0.77 (0.48; 1.24) | 0.85 (0.50; 1.45) | 1.11 (0.58; 2.12) |
former smoker | 0.91 (0.73; 1.14) | 1.04 (0.79; 1.35) | 0.96 (0.77; 1.21) | 0.99 (0.75; 1.31) | 0.89 (0.66; 1.21) | 0.83 (0.56; 1.22) | |
never-smoker | 1.00(referent) | 1.00(referent) | 1.00(referent) | 1.00(referent) | 1.00(referent) | 1.00(referent) | |
Body Mass Index | ≥30 kg/m2, n (%) | 1.57 (1.22; 2.00) | 1.48 (1.13; 1.94) | 1.51 (1.18; 1.93) | 1.52 (1.15; 2.01) | 1.87 (1.37; 2.56) | 1.98 (1.37; 2.85) |
History of Co-morbidity, | hypertension | 1.60 (1.29; 1.99) | 1.28 (1.00; 1.63) | 1.59 (1.27; 1.98) | 1.23 (0.96; 1.59) | 2.08 (1.53; 2.84) | 1.54 (1.07; 2.21) |
myocardial infarct | 2.40 (1.66; 3.46) | 2.18 (1.45; 3.26) | 2.84 (1.96; 4.10) | 2.40 (1.59; 3.62) | 3.23 (2.15; 4.84) | 2.22 (1.39; 3.56) | |
heart failure | 1.49 (1.11; 2.01) | 1.12 (0.80; 1.55) | 1.45 (1.08; 1.96) | 1.03 (0.74; 1.45) | 2.41 (1.70; 3.41) | 1.90 (1.27; 2.84) | |
diabetes | 1.59 (1.17; 2.15) | 1.37 (0.98; 1.92) | 1.43 (1.09; 1.94) | 1.14 (0.80; 1.62) | 1.67 (1.14; 2.44) | 1.14 (0.74; 1.77) | |