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Table 2 Association between the main outcomes of the cervical screening tests based on visual inspection methods and HIV status in Abidjan, Côte d'Ivoire.

From: Cervical cancer screening by visual inspection in Côte d'Ivoire, operational and clinical aspects according to HIV status

  

Univariate

Multivariate*

 

n/N

OR

95% CI

p

OR

95% CI

p

Eligible women who underwent a cervical screening with acetic acid and Lugol iodine (n = 4,046)

Positive VI†

   

< 10-4

  

< 10-4

HIV-negative

41/1,048

1

  

1

  

HIV-positive

268/2,998

2.41

1.72-3.37

 

2.28

1.61-3.23

 

Positive VIA

   

< 10-4

  

< 10-4

HIV-negative

20/1,048

1

  

1

  

HIV-positive

230/2,998

4.27

2.69-6.78

 

4.02

2.49-6.48

 

Positive VILI

   

< 10-4

  

< 10-4

HIV-negative

37/1,048

1

  

1

  

HIV-positive

255/2,998

2.54

1.79-3.61

 

2.34

1.63-3.36

 

Clinical cervicitis

   

< 10-3

  

< 10-4

HIV-negative

64/1,048

1

  

1

  

HIV-positive

290/2,998

1.65

1.24-2.18

 

1.86

1.38-2.50

 

No visualisation of the SCJ

   

0.47

  

0.45

HIV-negative

24/1,048

1

  

1

  

HIV-positive

81/2,998

1.18

0.75-1.88

 

1.2

0.74-1.94

 

CIN of any grade‡

   

10-3

  

< 10-2

HIV-negative

20/1,048

1

  

1

  

HIV-positive

132/2,998

2.36

1.47-3.81

 

2.13

1.31-3.45

 

Positively screened women with acetic acid and/or Lugol iodine (n = 309)

Multiple lesions

   

0.08

  

0.10

HIV-negative

6/41

1

  

1

  

HIV-positive

74/268

2.25

0.90-5.51

 

2.13

0.85-5.35

 

Lesions with several

   

< 10-4

  

< 10-4

quadrants of the cervix

       

involved

       

HIV-negative

14/41

1

  

1

  

HIV-positive

184/268

4.22

2.11-8.47

 

4.49

2.17-9.28

 

Extension to the endocervical canal

   

< 10-2

  

0.02

HIV-negative

11/41

1

  

1

  

HIV-positive

134/268

2.64

1.27-5.50

 

2.42

1.15-5.08

 

Patients lost to follow-up∫

  

0.32

   

0.26

HIV-negative

5/41

1

  

1

  

HIV-positive

50/268

1.65

0.62-4.42

 

1.89

0.63-5.69

 
  1. The IeDEA West Africa collaboration, 2009-2010.
  2. * Adjusted for age group in years ([25-35],[35-45],[45-55] and [55-65]), parity (yes vs. no) and number of lifetime sexual partners (< 5 vs. ≥5)
  3. † Positive visual inspection with VIA and/or VILI
  4. ‡ Histological precancerous or cancer lesions confirmed in women who underwent colposcopic examination and directed biopsies
  5. ∫ Positively screened women referred for a colposcopic consultation who did not attend the appointment after a telephone-based tracking procedure
  6. Abbreviations: OR Odds ratio, CI Confidence interval, VIA Visual inspection with acetic acid, VILI Visual inspection with Lugol iodine, SCJ Squamocolumnar junction, CIN Cervical intraepithelial neoplasia.