Figure 2

Forest plot of studies and pooled estimate of relative risk of renal disease. In (a) HIV-infected versus HIV-uninfected people; (b) HIV-infected people exposed to antiretroviral treatment versus treatment-naïve PLHIV; (c) HIV-infected people exposed to tenofovir-based ART versus non-tenofovir-based ART; (d) HIV-infected people per year of exposure to TDF-based ART. (e)Relative risk of renal disease in PLHIV according to CD4 count. Mid-values of the range of reported CD4 categories are plotted; each point/bar presents data from a single study, illustrating the RR/95% CI of CKD < 60 for the low CD4 group (CD4 value shown on the abscissa) compared to the high CD4 group (presented in Table 3). (f)Forest plot of studies and pooled estimate of relative risk of renal disease among people in AIDS stage versus non-AIDS HIV infection. (g)Relative risk of renal disease in HIV-infected people in various age groups (presented in Table 2). ¹Crane, 2007; compared with < 30, ²Lucas, 2007; compared with < 30, ³Ganesan, 2010; compared with < 35 ⁴Franey, 2009; compared with < 30; ⁵Lucas, 2007; compared with < 50; ⁶Campbell, 2009; compared with < 50. (h)Forest plot of studies and pooled estimate of relative risk of renal disease in HIV-infected people by 10-year increment in age.