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Table 8 Biomarker levels (median and inter-quartile range (IQR) for proxy-reported alcohol drinking behaviour

From: Alcohol and premature death in Estonian men: a study of forensic autopsies using novel biomarkers and proxy informants

Alcohol drinking behaviour of subject before death

Biomarker

 

Ethanol (blood)

mg/g

Ethanol (urine) mg/g

AST (serum) U/L

ALT (serum) U/L

GGT (serum) U/L

PEth (blood) μmol/L

EtG (urine)mg/L

EtS (urine) mg/L

 

N

Median (IQR)

N

Median (IQR)

N

Median (IQR)

N

Median (IQR)

N

Median (IQR)

N

Median (IQR)

N

Median (IQR)

N

Median (IQR)

Frequency of drinking any alcohol during last year

Every day /

almost every day

45

0.63

(0-2.0)

30

0.7

(0-2.9)

29

1558

(562-3210)

29

929

(237-2725)

29

193

(116-526)

44

9.7

(4.1-19.7)

26

78.3

(4.6-179)

26

23.1

(0-439)

1-4 times per

week

46

0

(0-2.1)

40

0.6

(0-3.4)

30

972

(551-1573)

30

985

(355-2618)

30

69

(49-122)

38

8.7

(2.6-16.1)

33

43.4

(4.3-246.9)

33

23.0

(0.09-350)

3 times per month

or more rarely

45

0

(0-2.1)

37

0

(0-2.2)

33

874

(467-2210)

33

910

(258-4675)

33

77

(62-111)

41

5.1

(0.5-19.0)

31

41.7

(0.2-338)

31

8.4

(0-198)

Never / almost

never

16

0

(0-0)

10

0

(0-0)

11

1686

(895-2384)

11

1856

(1393-3319)

11

69

(30-172)

11

0

(0-0.4)

4

0.1

(0-0.2)

4

0.01

(0-0.15)

P value for trend*

 

0.041

 

0.080

 

0.897

 

0.237

 

< 0.001

 

< 0.001

 

0.046

 

0.038

Drinking any alcohol during last month

Yes

80

0.2

(0-2.2)

58

0.6

(0-3.4)

54

1114

(634-3119)

54

988

(466-2940)

54

92

(57-168)

66

10.8

(4.3-22.9)

49

94.6

(4.6-338)

49

23.0

(1.1-69)

No

44

0

(0-2.0)

34

0

(0-2.2)

26

896

(399-1779)

26

885

(174-2725)

26

96

(66-172)

41

3.9

(0.2-10.3)

29

37.3

(0.3-172.2)

29

8.4

(0.1-49.8)

P value**

 

0.675

 

0.373

 

0.166

 

0.399

 

0.962

 

0.001

 

0.180

 

0.224

Drinking surrogates during last year

Yes

16

0.3

(0-1.8)

11

0

(0-3.1)

11

1558

(283-6208)

11

1031

(237-1951)

11

255

(86-511)

16

9.7

(3.4-18.5)

10

138.5

(2.7-771)

10

33.3

(0.6-98.7)

No

12

1

0

(0-2.1)

95

0

(0-2.9)

83

1036

(553-2604)

83

1078

(359-3810)

83

85

(52-163)

103

6.7

(1.2-15.5)

74

51.9

(2.5-246.9)

74

12.6

(0.7-53.7)

P value**

 

0.912

 

0.553

 

0.922

 

0.202

 

0.010

 

0.362

 

0.349

 

0.355

  1. *Regression method was applied for trend using log-values of biomarkers
  2. **T-test was applied using log-values of biomarker
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BMC Public Health

ISSN: 1471-2458

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