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Table 2 The estimated HRs and PARs of metabolic disorders and MetS for all-cause and CVD-related mortality in men and women

From: Age- and gender-specific population attributable risks of metabolic disorders on all-cause and cardiovascular mortality in Taiwan

All-cause mortality

 

Men

Women

 

Death (%) (N = 167)

Crude HR

(95% CI)

Adj HR†

(95% CI) ‡

p-value

PAR (%)

(95% CI) ‡

Death (%) (N = 91)

Crude HR

(95% CI)

Adj HR†

(95% CI) ‡

p-value

PAR (%)

(95% CI) ‡

MetS

58 (34.7)

1.89 (1.37-2.61)

1.50 (1.03-2.19)

0.02*

11.6 (2.5-22.5)

39 (42.9)

4.16 (2.76-6.12)

1.77 (1.08-2.89)

0.02*

18.6 (3.6-33.7)

High WC

64 (38.3)

1.23 (0.91-1.70)

1.07 (0.72-1.53)

0.74

2.4 (0.3-16.7)

56 (61.5)

3.20 (2.14-5.03)

1.49 (0.89-2.62)

0.17

20.2 (2.4 -43.5)

AH

94 (56.3)

3.40 (2.53-4.52)

1.88 (1.36-2.67)

0.0002*

26.4 (13.2-38.8)

50 (54.9)

5.36 (3.64-8.38)

2.19 (1.41-3.88)

0.002*

29.9 (13.5-47.5)

DM

35 (21.0)

2.83 (1.89-4.00)

1.70 (1.12-2.65)

0.007*

8.6 (2.0-16.4)

22 (24.2)

4.78 (2.85-7.45)

1.69 (0.95-2.85)

0.05

9.9 (0.7-20.1)

High TG

35 (21.0)

0.92 (0.61-1.33)

0.91 (0.60-1.34)

0.62

N/A§

20 (22.0)

2.34 (1.33-3.79)

1.19 (0.70-2.00)

0.53

3.5 (0.5-16.0)

Low HDL-C

50 (29.9)

1.46 (1.03-2.04)

1.72 (1.22-2.52)

0.002*

12.6 (4.5-21.8)

25 (27.5)

1.22 (0.71-1.89)

0.99 (0.57-1.55)

0.97

N/A§

CVD-related mortality#

 

Men

Women

 

Death (%) (N = 42)

Crude HR (95% CI)

Adj HR†

(95% CI) ‡

p-value

PAR (%)

(95% CI) ‡

Death (%) (N = 32)

Crude HR

(95% CI)

Adj HR†

(95% CI) ‡

p-value

PAR (%)

(95% CI) ‡

MetS

24 (57.1)

4.74 (2.42-9.28)

3.19 (1.55-7.58)

0.001*

39.2 (15.4-62.5)

20 (62.5)

9.24 (4.59-21.0)

3.45 (1.67-8.83)

0.003*

44.4 (18.7-69.8)

High WC

21 (50.0)

1.98 (1.05-3.69)

1.27 (0.57-2.66)

0.52

10.7 (1.4-40.6)

25 (78.1)

7.14 (3.38-24.3)

3.78 (1.79-13.6)

0.008*

57.5 (29.3-84.3)

AH

32 (76.2)

8.45 (4.19-20.0)

4.07 (1.84-9.98)

0.0005*

57.5 (28.6-79.6)

20 (62.5)

7.33 (3.54-16.4)

2.20 (1.03-5.50)

0.05*

34.1 (6.7-64.5)

DM

16 (38.1)

6.56 (3.29-12.9)

3.39 (1.51-8.61)

0.0004*

26.8 (8.3-48.5)

11 (34.4)

7.81 (3.52-16.6)

2.38 (0.98-5.70)

0.04*

19.9 (3.4-42.3)

High TG

13 (30.9)

1.56 (0.70-2.85)

1.29 (0.55-2.74)

0.47

6.9 (0.5-29.1)

11 (34.4)

4.34 (1.71-9.31)

1.97 (0.77-5.26)

0.10

16.9 (2.1-41.3)

Low HDL-C

15 (35.7)

1.89 (0.92-3.55)

2.07 (0.88-4.63)

0.03*

18.4 (3.0-38.9)

17 (53.1)

3.66 (1.81-7.90)

2.69 (1.25-6.51)

0.008*

33.4 (9.0-59.7)

  1. †: Models were adjusted by age strata, CAD, stroke, BMI category, alcohol drinking, smoking, betel nut chewing, exercise, and income
  2. ‡: The 95% confidence interval (CI) obtained by taking the 2.5 and 97.5 percentiles of the recalculated PARs among one thousand bootstrapped datasets
  3. #: CVD-related mortality (ICD-9th revision codes 240-279 and 390-459)
  4. §: N/A: Not available. The adjusted HR was less than 1, yielding a negative corresponding PAR
  5. *: p-value < 0.05 for the adjusted HR
  6. BMI, body mass index; CAD, coronary artery disease; CI, confidence interval; CVD, cardiovascular disease; DM, diabetes mellitus; AH, arterial hypertension; HDL-C, high- density lipoprotein cholesterol; HR, hazard ratio; MetS, metabolic syndrome; PAR, population attributable risk; TG, triglycerides; WC, waist circumference
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BMC Public Health

ISSN: 1471-2458

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