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Table 2 The estimated HRs and PARs of metabolic disorders and MetS for all-cause and CVD-related mortality in men and women

From: Age- and gender-specific population attributable risks of metabolic disorders on all-cause and cardiovascular mortality in Taiwan

All-cause mortality
  Men Women
  Death (%) (N = 167) Crude HR
(95% CI)
Adj HR†
(95% CI) ‡
p-value PAR (%)
(95% CI) ‡
Death (%) (N = 91) Crude HR
(95% CI)
Adj HR†
(95% CI) ‡
p-value PAR (%)
(95% CI) ‡
MetS 58 (34.7) 1.89 (1.37-2.61) 1.50 (1.03-2.19) 0.02* 11.6 (2.5-22.5) 39 (42.9) 4.16 (2.76-6.12) 1.77 (1.08-2.89) 0.02* 18.6 (3.6-33.7)
High WC 64 (38.3) 1.23 (0.91-1.70) 1.07 (0.72-1.53) 0.74 2.4 (0.3-16.7) 56 (61.5) 3.20 (2.14-5.03) 1.49 (0.89-2.62) 0.17 20.2 (2.4 -43.5)
AH 94 (56.3) 3.40 (2.53-4.52) 1.88 (1.36-2.67) 0.0002* 26.4 (13.2-38.8) 50 (54.9) 5.36 (3.64-8.38) 2.19 (1.41-3.88) 0.002* 29.9 (13.5-47.5)
DM 35 (21.0) 2.83 (1.89-4.00) 1.70 (1.12-2.65) 0.007* 8.6 (2.0-16.4) 22 (24.2) 4.78 (2.85-7.45) 1.69 (0.95-2.85) 0.05 9.9 (0.7-20.1)
High TG 35 (21.0) 0.92 (0.61-1.33) 0.91 (0.60-1.34) 0.62 N/A§ 20 (22.0) 2.34 (1.33-3.79) 1.19 (0.70-2.00) 0.53 3.5 (0.5-16.0)
Low HDL-C 50 (29.9) 1.46 (1.03-2.04) 1.72 (1.22-2.52) 0.002* 12.6 (4.5-21.8) 25 (27.5) 1.22 (0.71-1.89) 0.99 (0.57-1.55) 0.97 N/A§
CVD-related mortality#
  Men Women
  Death (%) (N = 42) Crude HR (95% CI) Adj HR†
(95% CI) ‡
p-value PAR (%)
(95% CI) ‡
Death (%) (N = 32) Crude HR
(95% CI)
Adj HR†
(95% CI) ‡
p-value PAR (%)
(95% CI) ‡
MetS 24 (57.1) 4.74 (2.42-9.28) 3.19 (1.55-7.58) 0.001* 39.2 (15.4-62.5) 20 (62.5) 9.24 (4.59-21.0) 3.45 (1.67-8.83) 0.003* 44.4 (18.7-69.8)
High WC 21 (50.0) 1.98 (1.05-3.69) 1.27 (0.57-2.66) 0.52 10.7 (1.4-40.6) 25 (78.1) 7.14 (3.38-24.3) 3.78 (1.79-13.6) 0.008* 57.5 (29.3-84.3)
AH 32 (76.2) 8.45 (4.19-20.0) 4.07 (1.84-9.98) 0.0005* 57.5 (28.6-79.6) 20 (62.5) 7.33 (3.54-16.4) 2.20 (1.03-5.50) 0.05* 34.1 (6.7-64.5)
DM 16 (38.1) 6.56 (3.29-12.9) 3.39 (1.51-8.61) 0.0004* 26.8 (8.3-48.5) 11 (34.4) 7.81 (3.52-16.6) 2.38 (0.98-5.70) 0.04* 19.9 (3.4-42.3)
High TG 13 (30.9) 1.56 (0.70-2.85) 1.29 (0.55-2.74) 0.47 6.9 (0.5-29.1) 11 (34.4) 4.34 (1.71-9.31) 1.97 (0.77-5.26) 0.10 16.9 (2.1-41.3)
Low HDL-C 15 (35.7) 1.89 (0.92-3.55) 2.07 (0.88-4.63) 0.03* 18.4 (3.0-38.9) 17 (53.1) 3.66 (1.81-7.90) 2.69 (1.25-6.51) 0.008* 33.4 (9.0-59.7)
  1. †: Models were adjusted by age strata, CAD, stroke, BMI category, alcohol drinking, smoking, betel nut chewing, exercise, and income
  2. ‡: The 95% confidence interval (CI) obtained by taking the 2.5 and 97.5 percentiles of the recalculated PARs among one thousand bootstrapped datasets
  3. #: CVD-related mortality (ICD-9th revision codes 240-279 and 390-459)
  4. §: N/A: Not available. The adjusted HR was less than 1, yielding a negative corresponding PAR
  5. *: p-value < 0.05 for the adjusted HR
  6. BMI, body mass index; CAD, coronary artery disease; CI, confidence interval; CVD, cardiovascular disease; DM, diabetes mellitus; AH, arterial hypertension; HDL-C, high- density lipoprotein cholesterol; HR, hazard ratio; MetS, metabolic syndrome; PAR, population attributable risk; TG, triglycerides; WC, waist circumference