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Table 1 Assessments in the LIFE Child HEALTH and OBESITY cohorts

From: The LIFE child study: a life course approach to disease and health

 

LIFE Child HEALTH cohort

LIFE Child OBESITY cohort

Participant age

0-2 years

2-6 years

≥ 6 years

≥ 6 years

Anthropometry

· Weight

· Weight

· Weight

· Weight

· Height

· Height and sitting height

· Height and sitting height

· Height and sitting height

· Head, arm, leg, waist, neck, hip, thoracal and abdominal circumference

· Head, arm, leg, waist, neck and hip circumference

· Head, arm, leg, waist, neck and hip circumference

· Head, arm, leg, waist, neck and hip circumference

· Biparietal diameter

· Skinfolds

· Skinfolds

· Skinfolds

· Blood pressure

· Blood pressure

· Blood pressure

· Blood pressure

Clinical exam

· Clinical history (perinatal and past medical history, medications, immunisations, developmental history)

· Clinical history (perinatal and past medical history, medications, immunisations, developmental history)

· Clinical history (perinatal and past medical history, medications, immunisations, developmental history)

· Clinical history (perinatal and past medical history, medications, immunisations, developmental history, specific details relating to weight)

· Clinical examination including neurological examination and pubertal assessment

· Clinical examination including neurological examination and pubertal assessment

· Clinical examination including neurological examination and pubertal assessment

· Clinical examination including neurological examination and pubertal assessment

· Dental examination including dentition and early childhood caries

· Dental examination including dentition and early childhood caries

· Dental examination (jaw models, dental caries, periodontal disease, orofacial pain, bruxism and tongue function)

· Dental examination (jaw models, dental caries, periodontal disease, orofacial pain, bruxism and tongue function)

Biological samples

· Blood, urine and hair

· Blood, urine and hair

· Blood, urine and hair

· Oral glucose tolerance test

· Blood, urine and hair

Questionnaires

· See Table 4

· See Table 4

· See Table 4

· See Table 4

Motor and cognitive development

· Bayley scales

· Bayley scales (< 3.6 years)

· Motor skills test

· Motor skills test

· Motor skills test (> 3.6 years)

Imaging

· Cranial ultrasound (3rd month of life)

 

· 3D-Bodyscan1

· 3D-Bodyscan1

· Sonography (heart, intima media thickness, thyroid and kidney2, for a sub-sample)

· Sonography (heart, intima media thickness, thyroid and kidney2)

· Magnetic resonance imaging (for a sub-sample2)

Cardiovascular and pulmonary function tests

Spirometry

· Spiroergometry

· Spirometry

· Endopat (for a sub-sample)

Additional assessments

  

· Voice examination1

· Accelerometry

· Prick test1, 2 (LIFE Child ATOPY cohort)

· Resting electrocardiography

Optical coherence tomography and ophthalmoscopy2 (for a sub-sample)

· Indirect calorimetry (for a sub-sample)

· Voice examination

· Electrical bioimpedance analysis

· Polysomnography (for a sub-sample)

· Eating behaviour test2

· Optical coherence tomography and ophthalmoscopy2

    

Prick test1, 2 (LIFE Child ATOPY cohort)

  1. 1 The assessment is combined with a specific questionnaire. 2Planned.