From: The LIFE child study: a life course approach to disease and health
LIFE Child HEALTH cohort | LIFE Child OBESITY cohort | |||
---|---|---|---|---|
Participant age | 0-2 years | 2-6 years | ≥ 6 years | ≥ 6 years |
Anthropometry | · Weight | · Weight | · Weight | · Weight |
· Height | · Height and sitting height | · Height and sitting height | · Height and sitting height | |
· Head, arm, leg, waist, neck, hip, thoracal and abdominal circumference | · Head, arm, leg, waist, neck and hip circumference | · Head, arm, leg, waist, neck and hip circumference | · Head, arm, leg, waist, neck and hip circumference | |
· Biparietal diameter | · Skinfolds | · Skinfolds | · Skinfolds | |
· Blood pressure | · Blood pressure | · Blood pressure | · Blood pressure | |
Clinical exam | · Clinical history (perinatal and past medical history, medications, immunisations, developmental history) | · Clinical history (perinatal and past medical history, medications, immunisations, developmental history) | · Clinical history (perinatal and past medical history, medications, immunisations, developmental history) | · Clinical history (perinatal and past medical history, medications, immunisations, developmental history, specific details relating to weight) |
· Clinical examination including neurological examination and pubertal assessment | · Clinical examination including neurological examination and pubertal assessment | · Clinical examination including neurological examination and pubertal assessment | · Clinical examination including neurological examination and pubertal assessment | |
· Dental examination including dentition and early childhood caries | · Dental examination including dentition and early childhood caries | · Dental examination (jaw models, dental caries, periodontal disease, orofacial pain, bruxism and tongue function) | · Dental examination (jaw models, dental caries, periodontal disease, orofacial pain, bruxism and tongue function) | |
Biological samples | · Blood, urine and hair | · Blood, urine and hair | · Blood, urine and hair | · Oral glucose tolerance test |
· Blood, urine and hair | ||||
Questionnaires | · See Table 4 | · See Table 4 | · See Table 4 | · See Table 4 |
Motor and cognitive development | · Bayley scales | · Bayley scales (< 3.6 years) | · Motor skills test | · Motor skills test |
· Motor skills test (> 3.6 years) | ||||
Imaging | · Cranial ultrasound (3rd month of life) | · 3D-Bodyscan1 | · 3D-Bodyscan1 | |
· Sonography (heart, intima media thickness, thyroid and kidney2, for a sub-sample) | · Sonography (heart, intima media thickness, thyroid and kidney2) | |||
· Magnetic resonance imaging (for a sub-sample2) | ||||
Cardiovascular and pulmonary function tests | Spirometry | · Spiroergometry | ||
· Spirometry | ||||
· Endopat (for a sub-sample) | ||||
Additional assessments | · Voice examination1 | · Accelerometry | ||
· Prick test1, 2 (LIFE Child ATOPY cohort) | · Resting electrocardiography | |||
Optical coherence tomography and ophthalmoscopy2 (for a sub-sample) | · Indirect calorimetry (for a sub-sample) | |||
· Voice examination | ||||
· Electrical bioimpedance analysis | ||||
· Polysomnography (for a sub-sample) | ||||
· Eating behaviour test2 | ||||
· Optical coherence tomography and ophthalmoscopy2 | ||||
Prick test1, 2 (LIFE Child ATOPY cohort) |