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Table 3 Quality assessment of trials of antihypertensive agents in pregnancies with mild to moderate hypertension

From: Impact of interventions to prevent and manage preeclampsia and eclampsia on stillbirths

  Quality Assessment Summary of Findings
     Directness No of events  
No of studies (ref) Design Limitations Consistency Generalizability to population of interest Generalizability to intervention of interest Intervention Control Relative Risk (95% CI)
Stillbirths: MODERATE/LOW outcome specific quality
18 RCT Small sample size, Placebo not used Consistent; Low heterogeneity (p=0.93); Results statistically insignificant 3 studies in developing countries Yes 18 16 1.14 (0.60, 2.17)
Perinatal mortality: MODERATE/LOW outcome specific quality
20 RCT Small sample size, Placebo not used Consistent; Low heterogeneity (p=0.97); Results statistically insignificant 3 studies in developing countries Yes 30 82 0.96 (0.60, 1.54)