Table 3 Quality assessment of trials of antihypertensive agents in pregnancies with mild to moderate hypertension
From: Impact of interventions to prevent and manage preeclampsia and eclampsia on stillbirths
| Â | Quality Assessment | Summary of Findings | ||||||
|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Directness | No of events | Â | ||
No of studies (ref) | Design | Limitations | Consistency | Generalizability to population of interest | Generalizability to intervention of interest | Intervention | Control | Relative Risk (95% CI) |
Stillbirths: MODERATE/LOW outcome specific quality | ||||||||
18 | RCT | Small sample size, Placebo not used | Consistent; Low heterogeneity (p=0.93); Results statistically insignificant | 3 studies in developing countries | Yes | 18 | 16 | 1.14 (0.60, 2.17) |
Perinatal mortality: MODERATE/LOW outcome specific quality | ||||||||
20 | RCT | Small sample size, Placebo not used | Consistent; Low heterogeneity (p=0.97); Results statistically insignificant | 3 studies in developing countries | Yes | 30 | 82 | 0.96 (0.60, 1.54) |