Effectiveness of interventions to screen and manage infections during pregnancy on reducing stillbirths: a review

BMC Public Health

Table 2 Quality assessment of trials of the evidence for prevention in malaria in pregnancy (IPTp and ITNs) used during first or second pregnancy for preventing stillbirths

Quality assessment						Summary findings
				Directness		Intervention		Control
No of studies	Design	Limitations	Consistency of results	Generalizability to population of interest	Generalizability to intervention of interest	Number of events	Denominator	Number of events	Denominator	RR (95% CI)
*IPTp for preventing stillbirths:* High outcome-specific quality
3	RCT		Consistent X² for heterogeneity (2 df) = 0.23	High	High	44	1,489	36	1,083	0.96 (0.62-1.50)
*ITNs for preventing stillbirths:* High outcome-specific quality
4	CRCT	Not blinded	Consistent X² for heterogeneity (3 df) = 0.03	High	High	Unknown	Unknown	Unknown	Unknown	0.67 (0.47-0.97)
*Effect of IPTp and ITNs combined on stillbirths :* Moderate outcome-specific quality
7	RCT/ CRCT		Consistent X² for heterogeneity (6 df) = 1.76	High	High	Unknown	Unknown	Unknown	Unknown	0.78 (0.59-1.03)

RCT: Randomized controlled trial: CRCT: Community randomized controlled trial: RR: Relative risk: CI: Confidence Interval

ISSN: 1471-2458