Table 1 Characteristics of included studies
Study ID (ref) | Country | Sample size (n) | Mean initial age (months) | Dose (mg/day) | Duration (weeks) | Mean initial height (cm) | Mean initial HAZ score | Grade (High, moderate and low) |
|---|---|---|---|---|---|---|---|---|
Hong 1992[33] | China | 102 | 0 | 5 | 24 | 50.0 | -0.08 | Moderate |
Bates 1993[34] | Gambia | 110 | 18 | 70 (/2wk) | 64 | 76.8 | -1.57 | High |
Dirren 1994[35] | Ecuador | 96 | 32 | 10 | 64 | 81.6 | -2.89 | Moderate |
Castillo-Duran 1995[36] | Chile | 68 | 0 | 3 | 24 | 47.2 | -1.36 | Moderate |
Ninh 1996[37] | Vietnam | 146 | 17.5 | 10 | 20 | 71.3 | -2.91 | Moderate |
Sempertgui 1996[38] | Ecuador | 50 | 42.3 | 10 | 9 | _ | -2.00 | Moderate |
Ruz 1997[39] | Chile | 102 | 39.8 | 10 | 56 | 95.6 | -0.52 | High |
Rosado 1997 | Mexico | 109 | 28 | 20 | 52 | 83.4 | -1.55 | moderate |
Gardner 1998[42] | Jamaica | 61 | 14 | 10 | 12 | 68.7 | -2.85 | High |
Lira 1998[41] | Brazil | 137 | 0 | 1 and 5 | 8 | _ | _ | Moderate |
Kikafunda 1998[40] | Uganda | 155 | 55.8 | 10 | 24 | 103.3 | -0.70 | Moderate |
Rivera 1998[43] | Guatemala | 89 | 7.5 | 10 | 28 | 63.7 | -2.16 | High |
Smith 1999[44] | Belize | 51 | 44 | 70 | 24 | _ | _ | High |
Umeta 2000 [45] | Ethopia | 100 | 9.6 | 10 | 24 | 69.9 | -0.64 | High |
Castillo-Duran 2001[46] | Chile | 150 | 0 | 5 | 52 | 50.3 | -0.06 | High |
Dijkhuizen 2001[47] | Indonesia | 238 | 4.2 | 10 | 24 | 61.2 | -0.79 | High |
Osendarp 2002[48] | Bangladesh | 301 | 0.9 | 5 | 20 | 51.2 | 0.00 | Low |
Muller 2003 [49] | Burkina Faso | 709 | 18.5 | 24 | 75.5 | 8.7 | -1.55 | High |
Sur 2003[50] | India | 100 | 0 | 5 | 52 | 46.4 | -1.70 | High |
Black 2004[52] | Bangladesh | 94 | 6.5 | 20 | 24 | _ | -1.20 | Moderate |
Black 2004[53] | India | 200 | 1 | 5 | 32 | 47.5 | -1.20 | Moderate |
Lind 2004[54] | Indonesia | 340 | 6 | 10 | 24 | _ | -0.35 | High |
Alarcon 2004[51] | Peru | 213 | 17 | 3 | 18 | 76.8 | -1.04 | High |
Penny 2004[55] | Peru | 246 | 19 | 10 | 24 | 76.4 | -0.16 | High |
Gardner 2005[57] | Jamaica | 114 | 19 | 10 | 24 | 77.1 | -1.65 | Moderate |
Brooks2005[56] | Bangladesh | 1665 | 5.3 | 70(/wk) | 52 | 62.7 | -1.10 | High |
Wasantwist 2006[61] | Thailand | 304 | 4.5 | 10 | 24 | 62.3 | -0.70 | High |
Silva 2006 [60] | Brazil | 58 | 23.5 | 10 | 16 | _ | -1.95 | High |
Berger 2006[58] | Vietnam | 391 | 5.9 | 10 | 24 | 63.8 | -1.07 | High |
Olney 2006[59] | Tanzania | 433 | 8.8 | 10 | 52 | _ | -1.45 | Moderate |
Brown 2007[67] | Peru | 302 | 7.5 | 3 | 24 | 65.4 | -1.19 | High |
Fahmida 2007[62] | Indonesia | 399 | 5 | 10 | 24 | _ | -0.99 | High |
Wuehler 2008[64] | Ecuador | 253 | 21 | 3,7and10 | 24 | 77.4 | -2.30 | High |
Dijikhuizen 2008[63] | Multicentre trial (Thailand, Veitnam and Indonesia) | 2468 | 5.05 | 10 | 24 | _ | -0.82 | High |
Mozaffari-Khosarvi 2009[66] | Iran | 85 | 38.8 | 5 | 24 | _ | -1.65 | High |
Walker 2009 [65] | Bangladesh | 645 | 6.35 | 20 | 24 | 64.2 | _ | High |