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Table 1 Characteristics of included studies

From: Role of calcium supplementation during pregnancy in reducing risk of developing gestational hypertensive disorders: a meta-analysis of studies from developing countries

Study (ref)

Country

Target population

Baseline Calcium intake as Low

(< 900 mg/day), Adequate (>900g/day), Not specified)

Dose of Supplementation

(Cumulative dose)

Duration of supplementation

GRADE quality

Belizan et al 1991[37]

Argentina

Nulliparous pregnant women, < 20 weeks gestation. No comorbid

Low

2 g/day

< 20 weeks of pregnancy till delivery

High

Kumar et al 2009 [38]

India

Primigravida women with gestational age between 12-25 weeks

Low

2 g/day

12-25 weeks of pregnancy till delivery

High

L-Jaramillo et al. 1989[41]

Ecuador

Nulliparous pregnant women, < 24 weeks of gestation.

No comorbid

Low

2 g/day

23 weeks of pregnancy till delivery

Moderate

L-Jaramillo et al. 1990[40]

Ecuador

Nulliparous pregnant women in 28-30 weeks of gestation with positive roll over test

Low

2 g/day

28-30 weeks of pregnancy till delivery

Moderate

L-Jaramillo et al.1997[39]

Ecuador

Teenage (< 17.5 years) Nulliparous pregnant women < 20 weeks gestation. No comorbids or addiction

Low

2 g/day

20 weeks of pregnancy till delivery

High

Niromanesh et al. 2001[42]

Turkey

28-32 weeks pregnant women with positive roll over test and with at least one risk factor for pre-eclampsia. No chronic medical condition

Not specified

2 g/day

28-32 weeks of pregnancy till delivery

High

Purwar et al. 1996[43]

India

Nulliparous pregnant women < 20 weeks of gestation. No cormorbid

Low

2 g/day

20 weeks of pregnancy till delivery

High

Villar et al. 2006 [44]

Multicenter trial (Argentina, Egypt, India, Peru, South Africa and Vietnam)

Primiparous women < 20 weeks of gestation. No comorbids

Low

1.5 g/day

From enrollment till delivery

High

Taherian et al. 2002[46]

Iran

Nulliparous pregnant women < 20 weeks of gestation. No comrbids

Low

500 mg/day

From enrollment till delivery

Moderate

Wanchu et al. 2001[45]

India

Nulliparous pregnant women < 20 weeks of gestation. No known comorbids

Low

2 g/day

From enrollment till delivery

Moderate