Table 1 Results of pooled analysis and qualitative grading according to GRADE criteria for outcomes of interest for inclusion in the LiST:
From: Effect of balanced protein energy supplementation during pregnancy on birth outcomes
Quality Assessment | Summary of Findings | |||||||
|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Directness | No of patients | Effect | ||
No of studies | Design | Limitations | Consistency | Generalizability to Population of Interest | Generalizability to Intervention of interest | Intervention | Control | Relative Risk (95% CI) |
Impact of balance protein energy supplementation on small for gestational age: Quality of evidence - Moderate | ||||||||
RCTs / Cluster RCT/ Quasi RCTs | Two studies were quasi experimental trial. Sequence generation and allocation concealment was not adequate in some of the included studies. | No heterogeneity in the pooled data (I2 =0%). p= 0.65 | Studies conducted in both developed and developing countries. | Protein content of Supplement for intervention group ranged from 30 g to 44 g per day. The protein content provided < 25 % of total energy content. | 142 | 193 | 0.69 (0.56-0.85) | |
Impact of balance protein energy supplementation on neonatal mortality: Quality of evidence - Low | ||||||||
RCTs/ Cluster RCT/ Quasi RCTs | One quasi-experimental design. Allocation concealment was not adequate for one of the included cluster randomized controlled trial. Large loss to follow up in included studies. | No heterogeneity. (I2 =0) p=0.81 | One study from developed country and two from developing countries | Protein content of Supplement for intervention group ranged from 30 g to 44 g per day. The protein content provided < 25 % of total energy content. | 23 | 33 | 0.63 (0.37-1.06) | |