Skip to main content

Table 1 Definitions of interventions reviewed

From: Effect of case management on neonatal mortality due to sepsis and pneumonia

Oral antibiotic therapy alone
• Administration of oral antibiotics in the community for neonatal sepsis, meningitis, or pneumonia
Injection therapy alone
• Administration of intramuscular antibiotics, at home or in first-level facilities, for neonatal sepsis, meningitis, or pneumonia
Hospital-based management as an inpatient with supportive care
• Administration of intravenous antibiotics
Wider choice of antibiotics including broad spectrum antibiotics
Option of using frequent/higher dosage if needed to maintain high blood antibiotic levels or coverage for meningitis,
Access to second-line antibiotic therapy for neonates with treatment failure on first line antibiotics
• Intravenous access and administration of intravenous fluids if needed
• Oxygen supplementation if required
• Access to appropriate diagnostic procedures, such as monitoring of pulse, blood pressure, and oximetry reading, as well as monitoring/correction of hypoglycemia if required