Table 4 GRADE assessment of studies of the effect of Neonatal Resuscitation training in facilities on neonatal mortality from Intrapartum-related events (ie. “birth asphyxia”)
No of studies | Design | Limitations | Consistency | Generalizability to Population of Interest | Generalizability of intervention of interest | Post-InterventionEvents | Control- Baseline Events | Relative Risk (95% CI) |
|---|---|---|---|---|---|---|---|---|
Mortality ( Intrapartum-related Neonatal Deaths ) : Moderate outcome specific mortality | ||||||||
Before-and-after | Low quality | No evidence of heterogeneity (P=0.5) | Facility settings (ranging primary to tertiary care level), LIC-MIC | Advanced NRP in 2 studies, WHO Basic ENC in another | 360* | 185 | 0.70 (0.59, 0.84)a | |
Mortality ( Early Neonatal Deaths ) : Moderate outcome specific mortality | ||||||||
Before-and-after | Low quality | Strong evidence of heterogenity (P=0.002) | Facility settings (ranging primary to tertiary care level), LIC-MIC | Advanced NRP in 2 studies, WHO Basic ENC in another | 454* | 458 | 0.62 (0.41, 0.94)b | |
Morbidity ( Hypoxic Ischemic Encephalopathy ) : Low outcome specific morbidity | ||||||||
1 [2] | Before-and-after | Low quality | NA | Only 1 study, tertiary care hospital | Advanced NRP | 128* | 21 | 1.68 (1.06, 2.66)c |