Skip to main content

Table 5

From: Clean birth and postnatal care practices to reduce neonatal deaths from sepsis and tetanus: a systematic review and Delphi estimation of mortality effect

  

Quality Assessment

Summary of Findings

     

Generalisability

Intervention

Control

 

No of studies (ref)

Intervention

Design

Limitations

Consistency

To population of interest

To intervention of interest

No. Events

No. births

No. events

No. births

Effect size

(95% CI)

Neonatal Mortality (Tetanus Deaths):

 

1 (18)

CBK and education

Before and after

Low quality

 

Masai population*

Yes

0

1984

415

5716

RR = 0.01

(0.001 - 0.09)

1 (80)

CBK, TT plus multiple interventions

Before and after

Multiple interventions

 

India. Lady health worker delivered

Multiple interventions

0

1951

2

1958

OR = 0.20

(0.01 - 4.18)

Neonatal Mortality (Sepsis Deaths):

 

No studies identified

        

Neonatal Mortality (All Cause):

 

1 (81)

CBK plus multiple interventions

cRCT

Multiple interventions

 

Pakistan TBA delivered

Multiple interventions

340

10092

439

19432

aOR 0.71

(0.62 - 0.83)

1 (18)

CBK and education

Before and after

Low quality

 

Masai population*

Yes

99

1984

1984

5716

RR = 0.17

(0.13 - 0.23)

1 (80)

CBK, TT plus multiple interventions

Before and after

Multiple interventions

 

India lady health worker delivered

Multiple interventions

35

1951

45

1958

OR 0.78

(0.50 - 1.21)

Neonatal Sepsis incidence:

 

1 (84)

CBK and demonstration

Before and after

Observational

 

Papua New Guinea**

Yes

1

67

8

64

OR = 0.11

(0.01 - 0.84)

Cord infection/oomphalitis:

 

3 (56, 58, 59)

CBK use

Adopters vs non-adopters

Observational

Heterogeneous

Egypt, Tanzania, Nepal

Yes

    

aOR 0.08-0.45

1 (11)

Use of individual items in CBK

Adopters vs non-adopters

Observational

 

Nepal

Yes

    

soap aRR = 0.49 (0.43-0.56)^

  1. *Specific cultural practices and defined neonatal death as death occuring in first 6 weeks of life **Specific cultural practices
  2. ^ no effect of other components on multivariable analysis TT = tetanus toxoid vaccination