Parameter | Value | Parameter | Value |
---|
τ | 3.5 d-1 |
p
V
12
| 0.3 |
δ
A
| 0.142 |
p
V
21
| 0.06 |
δ12= δ21 (δ) | 0≤δ≤1 | µ | 0.244 d-1 |
δV1 | 0.8 | µ
A
| 0.244 d-1 |
δV2 | 0.9 | σ1 | 0.8 |
p
| 0.6 | σ2 | 0.4 |
p12, p21 | 0.3 |
d
| 0.002 d-1 |
p
V1
| 0.12 |
d
A
| 0.002 d-1 |
p
V2
| 0.36 | T* | 10d, 60d |
- The values used in the simulations reported here correspond to those reported in [23, 24] for influenza. See Section 2 and Appendix for descriptions of parameters. Although data pertain to mean field (homogeneous) models, a correspondence between these and network models of this paper - see Appendix - enables one to apply these parameters to the latter type of model. In particular, a relationship between the transmission coefficient of the mean field model, β, and the baseline transmission rate τ between individuals in contact, enables one to assign a value to τ via the mean field expression for the basic reproductive number R0, as described in the Appendix. For the simulations, with pre-vaccination rate V0 = 0.2, a value R0 = 1.9 was assumed, representative of seasonal influenza and close to the value R0 = 1.8 used in [25]. Without vaccination, the corresponding value of R0 would be 2.34 (see Table 5).