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Table 1 Parameter values.

From: Public health interventions for epidemics: implications for multiple infection waves

Parameter

Description

Value

Source

β

Baseline transmission rate of the sensitive infection

variable

 

1/µ E

Expose period (duration between exposure and start of infectiousness)

1.25 days

[4, 15–18]

1/γ

Duration of infectiousness

4 days

[4, 15, 16, 18, 19]

α

Rate of developing drug resistance following start of treatment

10-4 days-1

[16, 18]

δ T

Relative transmissibility of the sensitive infection following treatment

0.4

[15, 16, 18, 20]

δ r

Relative transmissibility of the resistant infection

0.8

[15, 16, 18]

p

Fraction of infectious individuals diagnosed for treatment or isolation

variable

 

q

Fraction of treated infectious individuals without isolation

variable

 

T c

Capacity for treatment and isolation of infectious individuals

variable

 

R 0

Basic reproduction number of the sensitive infection

variable

[3, 19, 20]

  1. Baseline values of the parameters used for simulations of the models with sources from published literature. For a given value of R0, the baseline transmission rate β can be calculated using the expression R0 = βS0/γ.