Skip to main content

Table 2 Fits to two single-cycle viral yield experiments (Figure 4)

From: Exploring the effect of biological delays in kinetic models of influenza within a host or cell culture

A/Udorn/307/72 (H3N2) [28]

Dista

c(h–1)

Ï„ L (h)

σ L

(h)

SSR

AICc

exp

(0)b

0

2.4 × 106

1200

—

830

4.86

16.7

δ

(0)

8.1 × 103

7.7 × 105

10.7

—

10.7

0.90

6.6

N

(0)

3.3 × 103

8.3 × 105

11.1

1.5 h

11.1

0.039

17.8

  

[2.5:4.4]c

[5.9:12.7]

[9.8:12.5]

[0.8:2.2]

   

lnN

(0)

3.4 × 103

8.2 × 105

10.9

0.15

10.9

0.041

18.1

  

[2.4:4.1]

[5.6:12.8]

[9.7:12.6]

[0.08:0.22]

   

exp

(0.2)

0

1036

1032

—

1032

5.79

17.8

δ

(0.2)

27000

1.8 × 106

11.4

—

11.4

1.73

10.5

N

(0.2)

4.8 × 103

2.6 × 106

14.0

2.7 h

14.0

0.068

21.1

  

[3.1:7.7]

[1.8:4.4]

[13.0:15.9]

[2.3:3.3]

   

lnN

(0.2)

5.3 × 103

5.2 × 106

19.3

0.37

19.3

0.144

25.6

  

[2.8:10]

[1.7:11.0]

[12.5:57.9]

[0.22:0.58]

   

A/NWS/33 (H1N1) [32]

Dist

c(h–1)

Ï„ L (h)

σ L

(h)

SSR

AICc

exp

(0)

0

1.4 × 1026

4.8 × 1023

—

3.3 × 1023

8.30

2.8

δ

(0)

1300

1.2 × 105

10.9

—

10.9

2.77

-11.4

N

(0)

4.7 × 102

1.5 × 105

12.7

2.5 h

12.7

0.090

-51.7

  

[3.8:5.7]

[1.1:2.2]

[11.5:14.1]

[2.1:3.0]

   

lnN

(0)

5.3 × 102

2.3 × 105

15.3

0.33

15.3

0.167

-43.6

  

[4.1:6.6]

[1.1:9.2]

[11.6:26.1]

[0.24:0.47]

   

exp

(0)

0

4.5 × 1031

9.1 × 1028

—

6.3 × 1028

11.0

6.5

δ

(0.2)

1.8 × 103

9.6 × 104

7.9

—

7.9

2.11

-15.0

N

(0.2)

9.3 × 102

3.8 × 105

14.4

3.0 h

14.4

0.099

-50.4

  

[3.9:11]

[1.1:5.9]

[11.6: 21.9]

[0.3:3.3]

   

lnN

(0.2)

1.1 × 103

1.2 × 106

23.8

0.44

23.8

0.22

-40.0

  

[0.79:1.4]

[0.37:6.0]

[15.3:109]

[0.32:0.71]

   
  1. a — Distribution used: exponential (exp), Dirac delta (δ), normal (N), and lognormal (lnN).
  2. b — Values in parantheses were held fixed
  3. c — 95% confidence intervals are given in brackets for the normal and lognormal fits.