Table 3 Pandemic 2009 H1N1 influenza vaccination coverage of pregnant women; available data per European country

Austria (76033)

0 to 24%. Based on personal estimation

Belgium (126886)

No exposure data available

Unknown to registry.

Czech Republic (118283)

No exposure data available

Unknown to registry.

Croatia (44794)

Only 20 pregnant women have undergone vaccination. Data from Croatian Institute of Public Health, Epidemiology unit

Denmark (62831)

Weekly for Pandemrix: 5770 up to February 2010. WCBA: 42546 up to February 2010.

Unknown to registry.

Finland (60187)

No exposure data available

51.2% of mothers giving birth October-December 2009 were vaccinated with Pandemrix according to the Finnish medical birth register.

France (823925)

No exposure data available. WBCA: 980000 women aged 18-44 years old were vaccinated.

1) 25 to 49%. Based on CoFluPreg study (maternity wards in Paris) [12]. 2) Vaccination was not yet available at the time of pandemic wave (weeks 30-38) for Isle de la Reunion [35].

22.7% up to January 2010. Data from French State Health Insurance Fund [9]. 37.1% between Oct 2009 and Feb 2010. Data from COFLUPREG study [12].

Germany (664219)

0 to 24%. Based on registry and the Robert Koch Institute

8.8% between week 47/2009 and 14/2010. Based on 65 pregnant women [15].

Greece (118234)

Weekly for Focetria (1382 up to January 2010) and Pandemrix (751 up to January 2010)

Hungary (96297)

17200 vaccinated

About 16% [10].

Ireland (73870)

Several cut-off points for combined Celvapan and Pandemrix vaccination doses (31093 by June 2010).

A cross-sectional telephone survey found an uptake of 67% in pregnant women (n = 1725)[36] while the National Summary of Pandemic Influenza Vaccination estimates a vaccination rate of 32.5% [37].

Italy (570428)

Weekly for Focetria (23016 up to week 23/2010)

Latvia (21708)

No vaccinations took place

No vaccinations took place

Malta (4136)

0 to 24%. Based on national vaccination register data (numerator: persons classified as pregnant when vaccinated, denominator: number of persons pregnant on 1/1/2009 [data for 2010 not yet available]

Netherlands (184641)

Focetria exposure n = 68400 (cut-off 09 Feb 2010), Pandemrix 0

No registration was done of pregnant women who were vaccinated. Currently a study is being undertaken to estimate the vaccine coverage and to determine if the vaccine coverage depended on gestational age or underlying illness. The study is being conducted by the RIVM and 14,000 women will be approached for this study.

Norway (61430)

An estimated 70% of the pregnant women were vaccinated. Monthly for Celvapan (49) for WCBA and Pandemrix (377528) for WCBA.

1) 50 to 74%. The estimates is based on a small web-based request to general practitioners, http://www.uib.no/isf/eyr

2) 75 to 99%. Based on vaccination registers vs. registers of pregnant women. In the national registering system for vaccines there is no box for pregnancy. The Pregnancy record, in use by all pregnant women is being filled in manually.

Poland (415681)

No vaccinations took place

No vaccinations took place

Portugal (99896)

0 to 24%. Based on national registry. Available national data from ACSS - Administração Central do Sistema de Saúde, IP

Slovakia (61158)

No exposure data available

Slovenia (21746)

262 vaccinated total

Spain (494944)

Weekly for Panenza (39183).

0 to 24%. Based on personal estimation.

4.7% uptake in Castilla and Leon regions [13].

Sweden (111076)

15195 pregnant women and 264326 WCBA were vaccinated in Stockholm county up to Feb 2010.

Switzerland (77789)

Unknown to registry.

United Kingdom (788417)

103680 doses of Pandemrix and 1141 doses of Celvapan. Likely an underestimation.

1) 50-74% were offered the vaccine according to primary care data from a UKTIS study [16]. 2) 25 to 49%. Guess/Estimate based on proportion of regional clinical at risk groups vaccinated.

Out of 2,061 women pregnant between September 2009 and January 2010, 64.8% were offered vaccination and 25.2% were vaccinated [16].