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Table 2 Poisson Regression on Demographic Risks, Temporal Trends, and Testing Effects Associated with Reported Pertussis Risk in the Greater Toronto Area, Canada

From: Pertussis resurgence in Toronto, Canada: a population-based study including test-incidence feedback modeling

 

Exclude Testing Volume

Include Testing Volume

Variable

IRR (95% C.I.)

P-value

IRR (95% C.I.)

P-value

Temporal Trends*

    

Seasonal Oscillation

---

0.04

---

< 0.001

Oscillation, 6-year Period

---

< 0.001

---

< 0.001

Demographic Characteristics

    

Female Gender

1.15 (1.06 to 1.24)

< 0.001

1.14 (1.05 to 1.23)

< 0.001

Age

    

0 to 4 years

57.76 (50.91 to 65.53)

< 0.001

38.59 (33.84 to 44.00)

< 0.001

5 to 9 years

17.16 (14.78 to 19.93)

< 0.001

17.34 (14.94 to 20.14)

< 0.001

10 to 14 years

13.14 (11.24 to 15.36)

< 0.001

14.81 (12.66 to 17.32)

< 0.001

15 to 19 years

3.57 (2.82 to 4.52)

< 0.001

4.30 (3.40 to 5.44)

< 0.001

20 and over

1 (referent)

---

1 (referent)

---

Testing Practices

    

Introduction of Novel, Highly Sensitive PCR (May 2005)

3.75 (3.44 to 4.09)

< 0.001

2.31 (2.09 to 2.55)

< 0.001

Test Submission Volume (per 10 additional test specimens)

---

---

1.57 (1.53 to 1.61)

< 0.001

Pseudo-R2

0.43

0.47

Akaike's Information Criterion

11325

10421

  1. NOTE: IRR, incidence rate ratio; CI, confidence interval.
  2. * P-values for oscillation based on sine and cosine terms for oscillation at yearly and 6-yearly intervals.