Table 2 Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for allergic disorders according to the number of siblings in 1745 pregnant women, Kyushu Okinawa Maternal and Child Health Study, Japan1
| Â | Wheeze | Asthma | Eczema | Rhinoconjunctivitis | ||||
|---|---|---|---|---|---|---|---|---|
| Â | Prevalence | OR (95% CI) | Prevalence | OR (95% CI) | Prevalence | OR (95% CI) | Prevalence | OR (95% CI) |
Total siblings | Â | Â | Â | Â | Â | Â | Â | |
0 (n = 94) | 9.6% | 1.00 | 5.3% | 1.00 | 11.7% | 1.00 | 26.6% | 1.00 |
1 (n = 788) | 11.0% | 1.07 (0.53-2.40) | 5.3% | 0.94 (0.39-2.82) | 11.8% | 0.84 (0.45-1.74) | 27.0% | 0.87 (0.54-1.46) |
2 (n = 688) | 9.9% | 0.88 (0.43-1.99) | 5.7% | 0.92 (0.37-2.78) | 13.4% | 0.94 (0.49-1.94) | 25.3% | 0.79 (0.48-1.32) |
≥ 3 (n = 175) | 10.3% | 0.75 (0.32-1.87) | 5.7% | 0.72 (0.24-2.45) | 17.1% | 1.31 (0.63-2.92) | 22.9% | 0.75 (0.42-1.38) |
   P for trend | 0.18 |  | 0.55 |  | 0.18 |  | 0.23 | |
Older siblings | Â | Â | Â | Â | Â | Â | Â | |
0 (n = 829) | 10.7% | 1.00 | 5.1% | 1.00 | 12.7% | 1.00 | 29.0% | 1.00 |
1 (n = 622) | 11.1% | 1.02 (0.72-1.44) | 6.6% | 1.22 (0.77-1.93) | 12.5% | 1.03 (0.74-1.41) | 22.8% | 0.71 (0.56-0.91) |
≥ 2 (n = 294) | 8.2% | 0.74 (0.45-1.20) | 4.4% | 0.79 (0.40-1.49) | 14.6% | 1.33 (0.89-1.98) | 23.8% | 0.77 (0.56-1.06) |
   P for trend | 0.34 |  | 0.77 |  | 0.21 |  | 0.03 | |
Younger siblings | Â | Â | Â | Â | Â | Â | Â | |
0 (n = 695) | 9.8% | 1.00 | 5.9% | 1.00 | 12.8% | 1.00 | 23.6% | 1.00 |
1 (n = 695) | 11.1% | 1.07 (0.75-1.53) | 4.5% | 0.72 (0.44-1.17) | 11.7% | 0.78 (0.56-1.09) | 27.8% | 1.22 (0.95-1.56) |
≥ 2 (n = 355) | 10.4% | 0.90 (0.57-1.39) | 6.8% | 1.02 (0.59-1.75) | 15.8% | 1.09 (0.74-1.58) | 26.8% | 1.18 (0.87-1.59) |
   P for trend | 0.71 |  | 0.86 |  | 0.91 |  | 0.21 | |