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Table 4 Cost and effectiveness of three strategies for tuberculosis control in Zambian newborns over 30 years, for the total cohort of 468,073 newborns

From: Cost-effectiveness of novel vaccines for tuberculosis control: a decision analysis study

Strategies

Total Costs

Direct Costs

Indirect Costs

TB Cases

TB Mortality

Ranked from least to most expensive with respect to total cost

$ million

$ million

$ million

  

After 5 years

Novel TB vaccine at birth

7.123

3.348

3.775

5,771

2,861

 

Status quo

8.154

3.539

4.615

6,643

3,215

 

Novel TB vaccine at birth with Booster

8.347

4.572

3.775

5,771

2,861

After 10 years

Novel TB vaccine at birth

16.702

5.721

10.981

11,608

6,452

 

Novel TB vaccine at birth with Booster

17.926

6.945

10.981

11,608

6,452

 

Status quo

18.754

5.980

12.774

12,592

6,896

After 20 years

Novel TB vaccine at birth with Booster

36.486

10.129

26.357

19,388

12,772

 

Novel TB vaccine at birth

37.459

9.330

28.129

20,366

13,380

 

Status quo

40.463

9.583

30.880

21,305

13,808

After 30 years

Novel TB vaccine at birth with Booster

50.876

11.930

38.946

23,694

17,368

 

Novel TB vaccine at birth

52.863

11.126

41.737

24,625

17,957

 

Status quo

56.481

11.377

45.104

25,557

18,379