Is a HIV vaccine a viable option and at what price? An economic evaluation of adding HIV vaccination into existing prevention programs in Thailand

Table 5 The results of threshold analysis present the HIV vaccine prices being cost-effective, classified by risk group

Vaccine prices (THB) being cost-effective at a WTP threshold 100,000 THB per QALY gained
Duration of protection	Lifetime			10 years 3 boosters with full course^†			5 years 6 boosters with full course^†
Vaccine efficacy	30%	50%	70%	30%	50%	70%	30%	50%	70%
Risk behavior changed*
General population aged 18 years old
Unchanged	4,400	7,900	12,000	1,100	2,700	4,300	-	730	1,600
Increased 10%	2,400	6,500	11,000	210	2,000	3,900	-	380	1,400
Increased 20%	-	4,500	9,600	-	1,100	3,400	-	-	1,100
Increased 30%	-	2,000	8,100	-	23	2,700	-	-	760
General population aged 30 years old
Unchanged	-	410	1,100	-	-	-	-	-	-
Increased 10%	-	180	960	-	-	-	-	-	-
Increased 20%	-	-	780	-	-	-	-	-	-
Increased 30%	-	-	550	-	-	-	-	-	-
FSW aged 29 years old
Unchanged	52,000	85,000	120,000	23,000	38,000	54,000	12,000	20,000	29,000
Increased 10%	-	37,000	92,000	-	16,000	41,000	-	8,000	22,000
Increased 20%	-	-	59,000	-	-	26,000	-	-	14,000
Increased 30%	-	-	22,000	-	-	9,500	-	-	4,500
IDU aged 26 years old
Unchanged	57,000	96,000	140,000	35,000	58,000	82,000	21,000	34,000	48,000
Increased 10%	22,000	69,000	120,000	14,000	42,000	73,000	7,600	25,000	43,000
Increased 20%	-	45,000	110,000	-	28,000	64,000	-	16,000	38,000
Increased 30%	-	24,000	93,000	-	15,000	56,000	-	8,400	33,000
MSM aged 26 years old
Unchanged	170,000	310,000	500,000	100,000	170,000	250,000	59,000	98,000	140,000
Increased 10%	-	40,000	260,000	-	24,000	140,000	-	14,000	82,000
Increased 20%	-	-	31,000	-	-	19,000	-	-	11,000
Increased 30%	-	-	-	-	-	-	-	-	-
Military male conscript aged 21 years old
Unchanged	2,200	5,500	8,900	150	1,600	3,100	-	160	1,000
Increased 10%	-	3,100	7,500	-	560	2,500	-	-	650
Increased 20%	-	320	5,800	-	-	1,800	-	-	240
Increased 30%	-	-	3,800	-	-	850	-	-	-

THB: Thai baht as of 2009 value; WTP: willingness to pay; QALY: quality adjusted life year; FSW: female sex worker; IDU: injecting drug user; MSM: men who have sex with men.
"-" HIV vaccine would not be cost-effective.
*Risk behavior changed due to vaccination (i.e. decrease in condom use and increase in needle sharing among injecting drug users)
^†The study assumed that each boosted revaccination required a full course and the revaccination was needed to maintain protection over a 30-year period.

ISSN: 1471-2458