Skip to main content

Table 5 The results of threshold analysis present the HIV vaccine prices being cost-effective, classified by risk group

From: Is a HIV vaccine a viable option and at what price? An economic evaluation of adding HIV vaccination into existing prevention programs in Thailand

Vaccine prices (THB) being cost-effective at a WTP threshold 100,000 THB per QALY gained
Duration of protection Lifetime 10 years 3 boosters with full course 5 years 6 boosters with full course
Vaccine efficacy 30% 50% 70% 30% 50% 70% 30% 50% 70%
Risk behavior changed*          
General population aged 18 years old          
Unchanged 4,400 7,900 12,000 1,100 2,700 4,300 - 730 1,600
Increased 10% 2,400 6,500 11,000 210 2,000 3,900 - 380 1,400
Increased 20% - 4,500 9,600 - 1,100 3,400 - - 1,100
Increased 30% - 2,000 8,100 - 23 2,700 - - 760
General population aged 30 years old          
Unchanged - 410 1,100 - - - - - -
Increased 10% - 180 960 - - - - - -
Increased 20% - - 780 - - - - - -
Increased 30% - - 550 - - - - - -
FSW aged 29 years old          
Unchanged 52,000 85,000 120,000 23,000 38,000 54,000 12,000 20,000 29,000
Increased 10% - 37,000 92,000 - 16,000 41,000 - 8,000 22,000
Increased 20% - - 59,000 - - 26,000 - - 14,000
Increased 30% - - 22,000 - - 9,500 - - 4,500
IDU aged 26 years old          
Unchanged 57,000 96,000 140,000 35,000 58,000 82,000 21,000 34,000 48,000
Increased 10% 22,000 69,000 120,000 14,000 42,000 73,000 7,600 25,000 43,000
Increased 20% - 45,000 110,000 - 28,000 64,000 - 16,000 38,000
Increased 30% - 24,000 93,000 - 15,000 56,000 - 8,400 33,000
MSM aged 26 years old          
Unchanged 170,000 310,000 500,000 100,000 170,000 250,000 59,000 98,000 140,000
Increased 10% - 40,000 260,000 - 24,000 140,000 - 14,000 82,000
Increased 20% - - 31,000 - - 19,000 - - 11,000
Increased 30% - - - - - - - - -
Military male conscript aged 21 years old          
Unchanged 2,200 5,500 8,900 150 1,600 3,100 - 160 1,000
Increased 10% - 3,100 7,500 - 560 2,500 - - 650
Increased 20% - 320 5,800 - - 1,800 - - 240
Increased 30% - - 3,800 - - 850 - - -
  1. THB: Thai baht as of 2009 value; WTP: willingness to pay; QALY: quality adjusted life year; FSW: female sex worker; IDU: injecting drug user; MSM: men who have sex with men.
  2. "-" HIV vaccine would not be cost-effective.
  3. *Risk behavior changed due to vaccination (i.e. decrease in condom use and increase in needle sharing among injecting drug users)
  4. The study assumed that each boosted revaccination required a full course and the revaccination was needed to maintain protection over a 30-year period.