Table 3 Scenario analyses
From: Cost-effectiveness of rotavirus vaccination in the Netherlands; the results of a consensus model
Scenario | ICER in €/QALY Total vaccination cost of €50 | ICER in €/QALY Total vaccination cost of €75 | ICER in €/QALY Total vaccination cost of €100 |
|---|---|---|---|
Base case | 7,965 | 46,717 | 85,468 |
Inclusion of herd protection for children up to 5 years of agea | CS | 28,383 | 58,441 |
GP incidence based on Goossens et al. [7] | 498 | 35,855 | 71,211 |
DALYs based on Mangen et al. [9] | 7,645 | 44,841 | 82,037 |
QALY decrements in children treated at home similar to cases visiting a GP | 5,823 | 34,156 | 62,489 |
No QALY decrements in children treated at home | 15,172 | 88,991 | 162,809 |
No waning | 4,117 | 37,503 | 70,888 |
Mortality rate for hospitalised cases of 0.09% | 4,627 | 27,140 | 49,653 |
Mortality rate for hospitalised cases of 0.055% | 5,854 | 34,334 | 62,813 |
Productivity elasticity of 25% | 16,184 | 54,936 | 93,688 |
No productivity elasticity | 4,976 | 43,728 | 82,480 |
Excluding indirect costs (productivity losses) | 19,921 | 58,672 | 97,424 |
No discounting | 4,846 | 38,419 | 71,992 |
Equal discounting at 3.5% | 8,587 | 51,892 | 95,197 |