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Table 4 Comparison of mortality by cause of death in HIV-infected cohort in the periods 1999-2002 and 2003-2006; Navarre, Spain.

From: Mortality by causes in HIV-infected adults: comparison with the general population

  Period 1999-2002 Period 2003-2006    
  Cases Rate per 1000 PY Cases Rate per 1000 PY Hazard ratio* (95% CI) P-value
All HIV-infected subjects        
   All-cause deaths 115 32.6 95 26.5 0.72 (0.54-0.96) 0.024
   AIDS deaths 62 17.6 44 12.3 0.63 (0.42-0.95) 0.026
   Non-AIDS related deaths 53 15.0 51 14.2 0.82 (0.54-1.23) 0.325
Liver disease 14 4.0 22 6.1 1.34 (0.66-2.72) 0.420
Non-AIDS defining cancer 10 2.8 7 2.0 0.47 (0.17-1.30) 0.145
Drug overdoses or addiction 14 4.0 9 2.5 0.63 (0.26-1.53) 0.307
Cardiovascular disease 3 0.9 5 1.4 1.12 (0.25-5.06) 0.880
Suicide 3 0.9 4 1.1 1.26 (0.26-6.04) 0.776
Other external causes 3 0.9 1 0.3 0.21 (0.02-2.16) 0.190
All other causes 6 1.7 3 0.9 0.58 (0.13-2.50) 0.461
Injecting drug users        
   All-cause deaths 85 33.5 77 33.5 0.85 (0.60-1.19) 0.336
   AIDS deaths 43 16.9 31 13.5 0.68 (0.41-1.13) 0.132
   Non-AIDS related deaths 42 16.5 46 20.2 1.02 (0.65-1.61) 0.933
Non-injecting drug users        
   All-cause deaths 30 30.4 18 14.0 0.44 (0.24-0.79) 0.007
   AIDS deaths 19 19.3 13 10.1 0.49 (0.24-1.02) 0.057
   Non-AIDS related deaths 11 11.2 5 3.9 0.33 (0.11-0.96) 0.041
  1. PY, person-years. CI, confidence interval.
  2. *Hazard ratio obtained in Cox regression models with age as underlying time variable and adjusted for sex, country of origin (Spain or others) and injecting drug use.