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Table 4 Comparison of mortality by cause of death in HIV-infected cohort in the periods 1999-2002 and 2003-2006; Navarre, Spain.

From: Mortality by causes in HIV-infected adults: comparison with the general population

 

Period 1999-2002

Period 2003-2006

   
 

Cases

Rate per 1000 PY

Cases

Rate per 1000 PY

Hazard ratio*

(95% CI)

P-value

All HIV-infected subjects

       

   All-cause deaths

115

32.6

95

26.5

0.72

(0.54-0.96)

0.024

   AIDS deaths

62

17.6

44

12.3

0.63

(0.42-0.95)

0.026

   Non-AIDS related deaths

53

15.0

51

14.2

0.82

(0.54-1.23)

0.325

Liver disease

14

4.0

22

6.1

1.34

(0.66-2.72)

0.420

Non-AIDS defining cancer

10

2.8

7

2.0

0.47

(0.17-1.30)

0.145

Drug overdoses or addiction

14

4.0

9

2.5

0.63

(0.26-1.53)

0.307

Cardiovascular disease

3

0.9

5

1.4

1.12

(0.25-5.06)

0.880

Suicide

3

0.9

4

1.1

1.26

(0.26-6.04)

0.776

Other external causes

3

0.9

1

0.3

0.21

(0.02-2.16)

0.190

All other causes

6

1.7

3

0.9

0.58

(0.13-2.50)

0.461

Injecting drug users

       

   All-cause deaths

85

33.5

77

33.5

0.85

(0.60-1.19)

0.336

   AIDS deaths

43

16.9

31

13.5

0.68

(0.41-1.13)

0.132

   Non-AIDS related deaths

42

16.5

46

20.2

1.02

(0.65-1.61)

0.933

Non-injecting drug users

       

   All-cause deaths

30

30.4

18

14.0

0.44

(0.24-0.79)

0.007

   AIDS deaths

19

19.3

13

10.1

0.49

(0.24-1.02)

0.057

   Non-AIDS related deaths

11

11.2

5

3.9

0.33

(0.11-0.96)

0.041

  1. PY, person-years. CI, confidence interval.
  2. *Hazard ratio obtained in Cox regression models with age as underlying time variable and adjusted for sex, country of origin (Spain or others) and injecting drug use.