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Table 4 Risk of incident myocardial infarction by number of cigarettes per day (cig/day), tar and nicotine yield per cigarette (mg/cig) and tar and nicotine intake per day (mg/day) in women: Hazard ratio (HR) and 95% confidence interval (95% CI)

From: Association of daily tar and nicotine intake with incident myocardial infarction: Results from the population-based MONICA/KORA Augsburg Cohort Study 1984 - 2002

Smoking habits Number of
participants
(N)
Number of
events
(N)
Age- and survey-adjusted
model*
HR (95% CI)
MI risk factor-adjusted
model+
HR (95% CI)
Never-smokers++ 2,613 49 1.00 1.00
Ex-smokers 693 15 1.95 (1.09-3.48) 1.93 (1.07-3.47)
Occasional smokers 139 2 1.56 (0.38-6.44) 1.60 (0.39-6.65)
Regular smokers     
   Number of cigarettes smoked per day     
Light smokers (1 - 19 cig/day) 480 8 1.83 (0.86-3.90) 1.68 (0.79-3.57)
Heavy smokers (≥ 20 cig/day) 272 6 3.76 (1.57-8.97) 3.86 (1.57-9.50)
   Tar yield per cigarette#     
1 - 12 mg/cig 328 5 1.52 (0.60-3.85) 1.60 (0.63-4.07)
≥ 13 mg/cig 424 9 3.35 (1.62-6.94) 2.74 (1.31-5.72)
   Nicotine yield per cigarette#     
0.1 - 0.8 mg/cig 300 5 1.58 (0.63-3.98) 1.67 (0.66-4.24)
≥ 0.8 mg/cig 452 9 3.22 (1.55-6.68) 2.63 (1.26-5.50)
   Tar intake per day#     
1 - 129 mg/day 324 4 1.27 (0.46-3.54) 1.31 (0.47-3.65)
130 - 259 mg/day 238 5 2.72 (1.08-6.88) 2.30 (0.90-5.87)
≥ 260 mg/day 190 5 5.37 (2.07-13.94) 4.67 (1.76-12.40)
   Nicotine intake per day#     
1 - 8 mg/day 368 4 1.09 (0.39-3.03) 1.01 (0.36-2.81)
9 - 16 mg/day 235 6 3.84 (1.62-9.12) 3.88 (1.61-9.35)
≥ 17 mg/day 149 4 5.88 (2.06-16.76) 5.55 (1.88-16.35)
  1. ++ Reference category, * Model was adjusted for age (continuous) and survey (S1 or S2), model was additionally adjusted for alcohol consumption per day (0, 1-19, ≥ 20 g/day), actual hypertension (yes or no), total cholesterol/HDL-C ratio (<3.0, 3.0-5.4, ≥ 5.5), physical inactivity (yes or no) and diabetes (no or yes), # HRs and 95% CIs for ex- and occasional smokers from model including number of cigarettes smoked per day are displayed. The respective estimates in the models including tar yield, nicotine yield, tar or nicotine intake differ slightly and are almost equal.