From: Chronic occupational exposure to hexavalent chromium causes DNA damage in electroplating workers
variables | 8-OHdG | OTL# | Tail Length | Tail DNA% | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
 | exposed workers | control subjects | Pvaluea | exposed workers | control subjects | Pvaluea | exposed workers | control subjects | Pvaluea | exposed workers | control subjects | Pvaluea |
overall | 13.65 (3.08-66.30) | 8.31 (2.94-30.83) | <0.001 | 1.13 (0.14-6.77) | 0.14 (0.01-0.39) | <0.001 | 11.77 (3.46-52.19) | 3.26 (3.00-4.00) | <0.001 | 3.69 (0.65-16.20) | 0.69 (0.04-2.74) | <0.001 |
gender | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
male | 13.10 (3.08-66.30) | 7.51 (2.94-22.34) | <0.001 | 1.25 (0.14-6.77) | 0.14 (0.03-0.39) | <0.001 | 13.09 (3.46-52.19) | 3.26 (3.00-4.00) | <0.001 | 4.05 (0.74-16.20) | 0.69 (0.10-2.74) | <0.001 |
female | 14.71 (3.49-33.90) | 9.95 (3.55-30.83) | 0.006 | 0.90 (0.16-3.52) | 0.11 (0.01-0.23) | 0.002 | 9.43 (3.72-26.97) | 3.25 (3.00-4.00) | <0.001 | 3.05 (0.65-11.17) | 0.67 (0.04-1.20) | <0.001 |
P valueb | 0.41 | 0.06 | Â | 0.07 | 0.68 | Â | 0.011 | 0.964 | Â | 0.065 | 0.974 | Â |
age | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
<30 | 10.91 (4.51-27.28) | 5.07 (3.55-7.11) | <0.001 | 0.79 (0.16-2.78) | 0.07 (0.01-0.12) | 0.003 | 8.80 (3.69-27.97) | 3.20 (3.00-4.00) | <0.001 | 2.68 (0.65-8.02) | 0.44 (0.09-1.11) | 0.001 |
30-40 | 13.38 (3.49-59.15) | 8.66 (2.94-22.34) | 0.03 | 1.34 (0.14-6.77) | 0.09 (0.05-0.27) | <0.001 | 13.09 (3.46-52.19) | 3.26 (3.00-4.00) | <0.001 | 4.30 (0.74-16.20) | 0.72 (0.13-1.74) | <0.001 |
>40 | 14.59 (3.08-66.30) | 10.02 (3.30-30.83) | 0.05 | 1.06 (0.24-4.26) | 0.16 (0.08-0.39) | <0.001 | 11.59 (3.87-35.97) | 3.27 (3.00-4.00) | <0.001 | 3.51 (1.19-12.74) | 0.77 (0.04-2.74) | <0.001 |
P valueb | 0.52 | 0.001 | Â | 0.06 | 0.67 | Â | 0.038 | 0.947 | Â | 0.082 | 0.493 | Â |
smoking status | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
No | 9.65 (3.08-32.32) | 8.20 (2.94-22.34) | 0.04 | 1.07 (0.16-6.77) | 0.12 (0.01-0.27) | <0.001 | 11.19 (3.72-52.19) | 3.11 (3.00-4.00) | <0.001 | 3.46 (0.65-16.20) | 0.57 (0.04-1.32) | <0.001 |
Yes | 16.38 (3.49-66.30) | 8.40 (3.30-30.83) | <0.001 | 1.21 (0.14-4.26) | 0.18 (0.03-0.39) | <0.001 | 12.64 (3.46-35.97) | 3.33 (3.00-4.00) | <0.001 | 4.02 (0.74-12.74) | 0.75 (0.13-2.74) | <0.001 |
P valueb | <0.001 | 0.50 | Â | 0.32 | 0.57 | Â | 0.249 | 0.223 | Â | 0.200 | 0.471 | Â |
alcohol consumption | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
no | 12.28 (4.09-59.15) | 7.74 (2.94-30.83) | 0.03 | 1.06 (0.16-6.77) | 0.11 (0.01-0.23) | <0.001 | 10.95 (3.72-52.19) | 3.19 (3.00-4.00) | <0.001 | 3.44 (0.65-16.20) | 0.68 (0.04-2.74) | <0.001 |
yes | 15.12 (3.08-66.30) | 9.22 (3.30-22.34) | <0.001 | 1.21 (0.14-4.26) | 0.14 (0.05-0.39) | <0.001 | 12.73 (3.46-35.97) | 3.36 (3.00-4.00) | <0.001 | 3.99 (0.74-12.74) | 0.71 (0.22-1.74) | <0.001 |
P valueb | 0.05 | 0.57 | Â | 0.16 | 0.46 | Â | 0.064 | 0.314 | Â | 0.159 | 0.430 | Â |