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Table 2 Number of isolates by isolate characteristics and type of county DOT program.

From: Does directly observed therapy (DOT) reduce drug resistant tuberculosis?

  Selective DOT county Universal DOT county       
  (n = 1207) (n = 514) Crude Adjusted1
Isolate characteristic No. (%) No. (%) OR (95% CI) p-value OR (95% CI) p-value
EMB/INH/RIF resistant2           
   No 1108 (92) 489 (95) 1.0   0.03 1.0   0.049
   Yes 95 (8) 25 (5) 1.7 (1.1, 2.6)   1.6 (1.1, 2.6)  
   Unknown 4          
Belongs to a resistant cluster3           
   No 927 (77) 454 (88) 1.0   <0.0001 1.0   <0.0001
   Yes 280 (23) 60 (12) 2.3 (1.7, 3.1)   2.1 (1.6, 2.9)  
Belongs to a two-isolate resistant cluster4           
   No 1024 (85) 495 (96) 1.0   <0.0001 1.0   <0.0001
   Yes 183 (15) 19 (4) 4.7 (2.9, 7.6)   4.3 (2.6, 7.0)  
  1. 1Adjusted for age, race, and HIV status.
  2. 2Resistant to EMB, INH, and/or RIF.
  3. 3Genotype-clustered with at least one isolate in cluster resistant to EMB, INH, and/or RIF.
  4. 4Genotype-clustered with at least two of the EMB-, INH- and/or RIF-resistant isolates having the same EMB-INH-RIF resistance pattern.