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Table 2 Number of isolates by isolate characteristics and type of county DOT program.

From: Does directly observed therapy (DOT) reduce drug resistant tuberculosis?

 

Selective DOT county

Universal DOT county

      
 

(n = 1207)

(n = 514)

Crude

Adjusted1

Isolate characteristic

No.

(%)

No.

(%)

OR

(95% CI)

p-value

OR

(95% CI)

p-value

EMB/INH/RIF resistant2

          

   No

1108

(92)

489

(95)

1.0

 

0.03

1.0

 

0.049

   Yes

95

(8)

25

(5)

1.7

(1.1, 2.6)

 

1.6

(1.1, 2.6)

 

   Unknown

4

         

Belongs to a resistant cluster3

          

   No

927

(77)

454

(88)

1.0

 

<0.0001

1.0

 

<0.0001

   Yes

280

(23)

60

(12)

2.3

(1.7, 3.1)

 

2.1

(1.6, 2.9)

 

Belongs to a two-isolate resistant cluster4

          

   No

1024

(85)

495

(96)

1.0

 

<0.0001

1.0

 

<0.0001

   Yes

183

(15)

19

(4)

4.7

(2.9, 7.6)

 

4.3

(2.6, 7.0)

 
  1. 1Adjusted for age, race, and HIV status.
  2. 2Resistant to EMB, INH, and/or RIF.
  3. 3Genotype-clustered with at least one isolate in cluster resistant to EMB, INH, and/or RIF.
  4. 4Genotype-clustered with at least two of the EMB-, INH- and/or RIF-resistant isolates having the same EMB-INH-RIF resistance pattern.