Table 3 Example of diagnostic codes with the highest and lowest positive predictive value (excerpted from additional file 1)
From: Accuracy of syndrome definitions based on diagnoses in physician claims
Example of diagnostic codes with the HIGHEST positive predictive value (PPV) | |||
|---|---|---|---|
Syndrome | ICD-9 code | Diagnostic label | PPV (95% CI) |
Fever1 | 82.8 | Tick-borne rickettsiosis not elsewhere classified | 1.00 (1.00, 1.00) |
88.8 | Other specified arthropod-borne diseases | 1.00 (1.00, 1.00) | |
Gastrointestinal1 | 7.1 | Giardiasis | 1.00 (1.00, 1.00) |
5.9 | Food poisoning not otherwise specified | 1.00 (1.00, 1.00) | |
Neurological1 | 323.0 | Encephalitis in viral disease classified elsewhere | 1.00 (1.00, 1.00) |
784.3 | Aphasia | 1.00 (1.00, 1.00) | |
Rash1 | 53.8 | Herpes zoster with unspecified complication | 1.00 (1.00, 1.00) |
695.2 | Erythema nodosum | 1.00 (1.00, 1.00) | |
Respiratory1 | 33.0 | Bordetella pertussis | 1.00 (1.00, 1.00) |
462.9 | Pharyngitis, acute not otherwise specified | 1.00 (1.00, 1.00) | |
ILI large-group2 | 487.0 | Influenza with pneumonia | 1.00 (1.00, 1.00) |
486.0 | Pneumonia, organism not otherwise specified | 1.00 (1.00, 1.00) | |
Example of diagnostic codes with the LOWEST positive predictive value (PPV) | |||
Syndrome | ICD-9 code | Diagnostic label | PPV (95% CI) |
Fever1 | 88.0 | Bartonellosis | 0.00 (0.00, 0.00) |
78.2 | Sweating fever | 0.00 (0.00, 0.00) | |
Gastrointestinal1 | 555.0 | Regional enteritis, small intestine | 0.00 (0.00, 0.00) |
1.1 | Cholera due to Vibrio cholerae El Tor | 0.00 (0.00, 0.00) | |
Neurological1 | 323.2 | Encephalitis in protozoal disease classified elsewhere | 0.00 (0.00, 0.00) |
53.0 | Herpes zoster with meningitis | 0.00 (0.00, 0.00) | |
Rash1 | 51.0 | Cowpox | 0.00 (0.00, 0.00) |
55.8 | Measles complications not otherwise specified | 0.00 (0.00, 0.00) | |
Respiratory1 | 20.4 | Secondary pneumonic plague | 0.00 (0.00, 0.00) |
79.8 | Hantavirus infection | 0.00 (0.00, 0.00) | |
ILI large-group2 | 490.0 | Bronchitis not otherwise specified | 0.00 (0.00, 0.00) |
465.8 | Acute upper respiratory infection, other multiple sites | 0.36 (0.08, 0.65) | |