Characteristic | Cases (N = 80) | Controls (N = 266) | p-value |
---|---|---|---|
At treatment initiation | Â | Â | Â |
   Male gender (n, %) | 65 (81) | 175 (66) | < 0.01 |
   Marital status (n, %)§ |  |  | 0.70 |
Single | 32 (59) | 101 (53) | Â |
Married | 21(39) | 85(45) | Â |
Other (widowed, divorced) | 1(2) | 4(2) | Â |
   Medical comorbidities (n,%)* | 13(16) | 30(11) | 0.23 |
   Cavity on chest x-ray (n,%)‡ | 32(46) | 101(43) | 0.65 |
   Age (mean, sd) | 33.2(13.6) | 34.5(14.3) | 0.47 |
   Weight at treatment initiation (mean, sd) | 55.1 (9.5) | 56.0 (9.4) | 0.46 |
   Habits (n, %)√ |  |  |  |
Tobacco use | 18 (23) | 42(16) | 0.16 |
Alcohol use | 2(3) | 6(2) | 0.89 |
Illicit drug use | 6(8) | 4(2) | < 0.01 |
During treatment | Â | Â | Â |
   Sputum smear conversion to negative by 3 months (n,%)†| 28(45) | 220 (87) | < 0.01 |
   Weight gain after two months of treatment (kg, sd)** | 2.6 (3.8) | 3.4 (3.6) | 0.09 |
   Weight gain over initial treatment period (5-6 months) (kg, sd)** | 3.8 (5.8) | 6.6 (5.3) | < 0.01 |
   Missed doses during intensive phase | 14(18) | 10(4) | < 0.01 |
   Hospitalization | 21(26) | 38(14) | 0.01 |