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Table 3 Multivariable-adjusted mixed linear models, demonstrating associations between educational attainment and longitudinal trajectories of mean diastolic blood pressure, Framingham Offspring Study, 1971-2001.

From: Associations of education with 30 year life course blood pressure trajectories: Framingham Offspring Study

   Model Adjustment
Sex (n) Education (Years) Age Age, Conventional Risk Factors Age, Baseline Blood Pressure Age, Baseline Blood Pressure, Conventional Risk Factors
Female (n = 2024) ≤12 1.47 (0.43, 2.50) 1.26 (0.25, 2.26) 0.62 (-0.31, 1.55) 0.51 (-0.42, 1.43)
  13-16 1.29 (0.26, 2.33) 1.40 (0.40, 2.40) 0.33 (-0.60, 1.26) 0.44 (-0.48, 1.36)
  ≥17 0 0 0 0
Male (n = 1866) ≤12 0.66 (-0.17, 1.50) 0.05 (-0.78, 0.86) 0.42 (-0.33, 1.18) -0.09 (-0.85, 0.68)
  13-16 0.60 (-0.23, 1.43) 0.14 (-0.68, 0.96) 0.49 (-0.27, 1.24) 0.09 (-0.67, 0.85)
  ≥17 0 0 0 0
  1. Point estimates (and 95% confidence intervals shown in parentheses) represent mean differences in diastolic blood pressure (mmHg) between comparison and referent groups. Age adjustment refers to adjustment for baseline age and time from baseline age. Modeling for baseline age and time from baseline was as follows: age+age2+time+ time2+age*time+age*time2+age2*time+age2*time2.
  2. Conventional risk factors include antihypertensive medication, smoking, body mass index and alcohol consumption.