Skip to main content

Table 3 Associations between maternal perinatal depression and childhood infections with antibiotic treatment

From: Association between perinatal depression in mothers and the risk of childhood infections in offspring: a population-based cohort study

 

Maternal perinatal depression

 

No

 

Yes

   

Antibiotic-treated childhood infections

Events

Rate per 10 person-years

(95% CI*)

Events

Rate per 10 person-years

(95% CI*)

Rate difference

(95% CI*)

Unadjusted IRR#

(95% CI*)

GI infections†

Age (years)

0-4

3550

0.10 (0.10-0.10)

512

0.15 (0.14-0.16)

0.05 (0.03-0.06)

1.47 (1.34-1.61)

   0-1

1144

0.12 (0.11-0.13)

176

0.18 (0.16-0.21)

0.07 (0.04-0.09)

1.54 (1.32-1.81)

   1-2

1153

0.13 (0.12-0.14)

172

0.19 (0.17-0.23)

0.07 (0.04-0.10)

1.52 (1.29-1.78)

   2-3

731

0.09 (0.08-0.09)

104

0.12 (0.10-0.15)

0.04 (0.01-0.06)

1.45 (1.18-1.78)

   3-4

522

0.06 (0.06-0.07)

60

0.08 (0.06-0.10)

0.01 (0.00-0.03)

1.18 (0.90-1.54)

LRTIs‡

Age (years)

0-4

8868

0.25 (0.25-0.26)

1035

0.30 (0.28-0.32)

0.05 (0.03-0.07)

1.19 (1.11-1.27)

   0-1

3462

0.36 (0.35-0.37)

418

0.44 (0.40-0.48)

0.07 (0.03-0.12)

1.21 (1.10-1.34)

   1-2

2536

0.28 (0.27-0.29)

276

0.31 (0.28-0.35)

0.03 (0.00-0.07)

1.11 (0.98-1.25)

   2-3

1661

0.20 (0.19-0.21)

195

0.23 (0.20-0.27)

0.04 (0.00-0.07)

1.20 (1.03-1.39)

   3-4

1209

0.15 (0.14-0.16)

146

0.19 (0.16-0.22)

0.04 (0.00-0.07)

1.24 (1.04-1.47)

  1. * Confidence interval
  2. # Incidence rate ratio
  3. † Gastrointestinal infections
  4. ‡Lower respiratory tract infections