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Table 3 Associations between maternal perinatal depression and childhood infections with antibiotic treatment

From: Association between perinatal depression in mothers and the risk of childhood infections in offspring: a population-based cohort study

  Maternal perinatal depression
  No   Yes    
Antibiotic-treated childhood infections Events Rate per 10 person-years
(95% CI*)
Events Rate per 10 person-years
(95% CI*)
Rate difference
(95% CI*)
Unadjusted IRR#
(95% CI*)
GI infections
Age (years)
0-4 3550 0.10 (0.10-0.10) 512 0.15 (0.14-0.16) 0.05 (0.03-0.06) 1.47 (1.34-1.61)
   0-1 1144 0.12 (0.11-0.13) 176 0.18 (0.16-0.21) 0.07 (0.04-0.09) 1.54 (1.32-1.81)
   1-2 1153 0.13 (0.12-0.14) 172 0.19 (0.17-0.23) 0.07 (0.04-0.10) 1.52 (1.29-1.78)
   2-3 731 0.09 (0.08-0.09) 104 0.12 (0.10-0.15) 0.04 (0.01-0.06) 1.45 (1.18-1.78)
   3-4 522 0.06 (0.06-0.07) 60 0.08 (0.06-0.10) 0.01 (0.00-0.03) 1.18 (0.90-1.54)
LRTIs
Age (years)
0-4 8868 0.25 (0.25-0.26) 1035 0.30 (0.28-0.32) 0.05 (0.03-0.07) 1.19 (1.11-1.27)
   0-1 3462 0.36 (0.35-0.37) 418 0.44 (0.40-0.48) 0.07 (0.03-0.12) 1.21 (1.10-1.34)
   1-2 2536 0.28 (0.27-0.29) 276 0.31 (0.28-0.35) 0.03 (0.00-0.07) 1.11 (0.98-1.25)
   2-3 1661 0.20 (0.19-0.21) 195 0.23 (0.20-0.27) 0.04 (0.00-0.07) 1.20 (1.03-1.39)
   3-4 1209 0.15 (0.14-0.16) 146 0.19 (0.16-0.22) 0.04 (0.00-0.07) 1.24 (1.04-1.47)
  1. * Confidence interval
  2. # Incidence rate ratio
  3. Gastrointestinal infections
  4. Lower respiratory tract infections