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Table 2 Associations between maternal perinatal depression and childhood gastrointestinal infections and childhood lower respiratory infections

From: Association between perinatal depression in mothers and the risk of childhood infections in offspring: a population-based cohort study

 

Maternal perinatal depression

 

No

 

Yes

   

Childhood infections

Events

Rate per 10 person-years

(95% CI*)

Events

Rate per 10 person-years

(95% CI*)

Rate difference

(95% CI*)

Unadjusted IRR#

(95% CI*)

GI infections†

Age (years)

0-4

84999

2.44 (2.43-2.46)

11634

3.41 (3.35-3.47)

0.97 (0.90-1.03)

1.40 (1.37-1.42)

   0-1

34928

3.71 (3.67-3.75)

4950

5.31 (5.16-5.46)

1.60 (1.45-1.75)

1.43 (1.39-1.48)

   1-2

26845

3.02 (2.98-3.06)

3533

4.06 (3.93-4.19)

1.04 (0.90-1.18)

1.34 (1.30-1.39)

   2-3

14289

1.69 (1.66-1.72)

1981

2.40 (2.30-2.51)

0.71 (0.60-0.82)

1.42 (1.35-1.49)

   3-4

8937

1.11 (1.09-1.13)

1170

1.49 (1.41-1.58)

0.38 (0.30-0.47)

1.35 (1.27-1.43)

LRTIs‡

Age (years)

0-4

25143

0.72 (0.71-0.73)

3139

0.91 (0.88-0.94)

0.19 (0.16-0.23)

1.27 (1.22-1.32)

   0-1

12202

1.28 (1.26-1.31)

1632

1.72 (1.64-1.81)

0.44 (0.36-0.53)

1.35 (1.28-1.42)

   1-2

6530

0.73 (0.71-0.75)

725

0.82 (0.76-0.88)

0.09 (0.03-0.16)

1.13 (1.05-1.22)

   2-3

3783

0.45 (0.43-0.46)

454

0.55 (0.50-0.60)

0.10 (0.05-0.15)

1.23 (1.11-1.35)

   3-4

2628

0.33 (0.31-0.34)

328

0.42 (0.37-0.46)

0.09 (0.04-0.14)

1.28 (1.14-1.44)

  1. * Confidence interval
  2. # Incidence rate ratio
  3. † Gastrointestinal infections
  4. ‡ Lower respiratory tract infections