Worksite health screening programs for predicting the development of Metabolic Syndrome in middle-aged employees: a five-year follow-up study

Table 5 Model 3, adjusted risks for metabolic syndrome (MetS) calculated using each MetS component and their combinations as potential risk factors

Baseline MetS components and combinations*	Adjusted-OR**	95%CI	Overall (N = 1384) P	SI^†	95%CI
Adults having single MetS component at baseline	NA ^‡	-	-	-	-
COB alone	9.1	2.8 - 29.9	<0.01	one risk alone	-
Hyper-TG alone	3.4	1.5 - 7.7	<0.01	one risk alone	-
Hyper-GL alone	3.0	1.5 - 6.0	<0.01	one risk alone	-
Low-HDL alone	2.9	1.4 - 5.8	<0.01	one risk alone	-
HBP alone	1.4	0.6 - 3.4	0.44	one risk alone	-
Adults having two MetS components at baseline	NA
COB-plus-Hyper-TG	59.6	5.8 - 611.5	<0.01	7.6	0.8 - 74.5
COB-plus-Low-HDL	24.6	7.7 - 78.2	<0.01	2.8	0.8 - 9.2
COB-plus-HBP	14.5	3.6 - 59.1	<0.01	2.0	0.5 - 8.5
HBP-plus-Low-HDL	11.7	5.1 - 27.0	<0.01	4.7	2.1 - 10.9
HBP-plus-Hyper-GL	7.9	3.5 - 18.1	<0.01	2.7	1.2 - 6.4
COB-plus-Hyper-GL	6.7	1.2 - 38.7	<0.05	0.8	0.1 - 5.2
HBP-plus-Hyper-TG	5.8	2.2 - 15.4	<0.01	1.6	0.6 - 4.3
Low-HDL-plus-Hyper-TG	5.7	2.7 - 12.3	<0.01	1.6	0.7 - 3.3
Hyper-GL-plus-Hyper-TG	4.1	1.5 - 11.1	<0.01	1.6	0.6 - 4.4
Hyper-GL-plus-Low-HDL	3.9	1.6 - 9.8	<0.01	1.1	0.4 - 2.9

* Abbreviations: Hyper-GL, hyperglycemia; Low-HDL, Low-HDL cholesterolemia; HBP, high blood pressure; Hyper-TG, hypertriglyceridemia; COB, central obesity.;.
** Adjusted variables were age and categorical variables including gender, smoking, diet habits, drinking, exercise status, liver enzymes, sonographic fatty liver, hepatovirus infections, hyperinsulinemia and hyperuricemia.
^† SI, synergistic index, SI value exceeding 1.0 indicates the presence of synergistic interaction.
^‡ NA: Not analyzed in this model, analyzed and shown in Table 4, Model 2.
SI and 95%CI in bold are considered to be statistically significant.

ISSN: 1471-2458