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Table 5 Model 3, adjusted risks for metabolic syndrome (MetS) calculated using each MetS component and their combinations as potential risk factors

From: Worksite health screening programs for predicting the development of Metabolic Syndrome in middle-aged employees: a five-year follow-up study

Baseline MetS components and combinations* Adjusted-OR** 95%CI Overall (N = 1384)
P
SI 95%CI
Adults having single MetS component at baseline NA - - - -
   COB alone 9.1 2.8 - 29.9 <0.01 one risk alone -
   Hyper-TG alone 3.4 1.5 - 7.7 <0.01 one risk alone -
   Hyper-GL alone 3.0 1.5 - 6.0 <0.01 one risk alone -
   Low-HDL alone 2.9 1.4 - 5.8 <0.01 one risk alone -
   HBP alone 1.4 0.6 - 3.4 0.44 one risk alone -
Adults having two MetS components at baseline NA     
   COB-plus-Hyper-TG 59.6 5.8 - 611.5 <0.01 7.6 0.8 - 74.5
   COB-plus-Low-HDL 24.6 7.7 - 78.2 <0.01 2.8 0.8 - 9.2
   COB-plus-HBP 14.5 3.6 - 59.1 <0.01 2.0 0.5 - 8.5
   HBP-plus-Low-HDL 11.7 5.1 - 27.0 <0.01 4.7 2.1 - 10.9
   HBP-plus-Hyper-GL 7.9 3.5 - 18.1 <0.01 2.7 1.2 - 6.4
   COB-plus-Hyper-GL 6.7 1.2 - 38.7 <0.05 0.8 0.1 - 5.2
   HBP-plus-Hyper-TG 5.8 2.2 - 15.4 <0.01 1.6 0.6 - 4.3
   Low-HDL-plus-Hyper-TG 5.7 2.7 - 12.3 <0.01 1.6 0.7 - 3.3
   Hyper-GL-plus-Hyper-TG 4.1 1.5 - 11.1 <0.01 1.6 0.6 - 4.4
   Hyper-GL-plus-Low-HDL 3.9 1.6 - 9.8 <0.01 1.1 0.4 - 2.9
  1. * Abbreviations: Hyper-GL, hyperglycemia; Low-HDL, Low-HDL cholesterolemia; HBP, high blood pressure; Hyper-TG, hypertriglyceridemia; COB, central obesity.;.
  2. ** Adjusted variables were age and categorical variables including gender, smoking, diet habits, drinking, exercise status, liver enzymes, sonographic fatty liver, hepatovirus infections, hyperinsulinemia and hyperuricemia.
  3. SI, synergistic index, SI value exceeding 1.0 indicates the presence of synergistic interaction.
  4. NA: Not analyzed in this model, analyzed and shown in Table 4, Model 2.
  5. SI and 95%CI in bold are considered to be statistically significant.
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