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Table 3 Persistent perinatal CMD and infant development

From: Maternal common mental disorders and infant development in Ethiopia: the P-MaMiE Birth Cohort

  Persistent perinatal CMD Categories of increasing exposure to perinatal CMD¥
  β ^ (95% Confidence Interval)  
Bayley sub-scale SRQ ≥ 6 in
pregnancy or 2
months postnatal§
SRQ ≥ 6 in
pregnancy & 2
months postnatal§
Test-for-trend Χ2(df); p-value
Cognitive    
Crude -0.99 (-2.12, 0.15) -1.59 (-3.99, 0.82) 6.66(1); p < 0.025
Fully adjusted* -0.64 (-1.79, 0.51) -2.11 (-4.87, 0.65) 2.58(1); p > 0.10
Motor    
Crude -0.80 (-2.24, 0.65) -4.19 (-8.60, 0.21) 13.08(1); p < 0.001
Fully adjusted* 0.15 (-1.52, 1.82) -4.15 (-9.19, 0.89) 2.83(1); p > 0.05
Language    
Crude -0.16 (-1.45, 1.13) -0.72 (-3.29, 1.85) 3.93(1); p < 0.05
Fully adjusted* 0.21 (-1.11, 1.53) -1.12 (-4.42, 2.17) 0.23(1); p > 0.50
  Persistent postnatal CMD Categories of increasing exposure to postnatal CMD
  β ^ (95% Confidence Interval)  
Bayley sub-scale SRQ ≥ 6 at postnatal 2 OR 12 months± SRQ ≥ 6 at postnatal 2 & 12 months± Test-for-trend Χ2 (df); p-value
Cognitive    
Crude 0.61 (-1.28, 2.51) -0.25 (-1.49, 0.99) 0.04(1); p > 0.50
Fully adjusted* 0.90 (-1.13, 2.93) 0.20 (-1.28, 1.67) 0.29(1); p > 0.50
Motor    
Crude -2.22 (-5.96, 1.52) -3.01 (-8.01, 2.00) 3.37(1); p > 0.10
Fully adjusted* -1.42 (-4.91, 2.07) -2.65 (-9.26, 3.96) 1.75(1); p > 0.10
Language    
Crude 2.16 (0.35, 3.96) -0.61 (-3.66, 2.44) 0.60(1); p > 0.25
Fully adjusted* 2.37 (0.18, 4.55) -0.56 (-4.01, 2.90) 0.74(1); p > 0.25
  1. Exploratory analyses showing association between persistent maternal common mental disorder (CMD) and infant Bayley scale scores at 12 months of age (n = 183 in adjusted model)
  2. § Reference category = SRQ < 6 in pregnancy and 2 months postnatal. ± Reference category = SRQ < 6 at 2 and 12 months postnatal. *Adjusted for all potential confounders. ¥No CMD, CMD in pregnancy or postnatal (2 months), CMD in both pregnancy and postnatal. No CMD, CMD in pregnancy or postnatal (12 months), CMD in both pregnancy and postnatal.