CT scan screening is associated with increased distress among subjects of the APExS

BMC Public Health

Table 3 Course of PCQ scores and proportions of subjects with abnormal PCQ score^a between T1 and T2 according to the HRCT scan results (n = 832, univariate analyses)

			At T1			At T2				Variation
CT scans	N	Abnormal PCQ^aN (%)	Mean PCQ	P value^b	Abnormal PCQ^aN (%)	Mean PCQ	P value^b	Acquiring Abnormal PCQ^aN (%)	P value ^c	Mean PCQ^d	P value^e
Normal	213	44 (20.7)	8.02	Reference	57 (26.8)	9.28	Reference	31 (14.6)	0.0633	+1.26	0.0010
Isolated pulmonary Nodules (only)	79	15 (19.0)	8.99	0.2019	27 (34.2)	10.58	0.1497	17 (21.5)	0.0105	+1.59	0.0276
Pleural plaques (only)	113	21 (18.6)	7.77	0.6972	40 (35.4)	11.24	0.0078	24 (21.2)	0.0004	+3.47	<0.0001
Asbestosis (with or without pleural plaques)	67	13 (19.4)	8.40	0.9280	26 (38.8)	10.64	0.1303	18 (26.9)	0.0067	+2.24	0.0005
Other diseases (only)	151	28 (18.5)	8.38	0.5490	53 (35.1)	10.19	0.2037	32 (21.2)	< 0.0001	+1.80	0.0002
Two or more of the above lesions	49	10 (20.4)	7.73	0.7504	21 (42.9)	10.86	0.1202	13 (26.5)	0.0045	+3.12	0.0002
Unknown results	160	40 (25.0)	8.79	0.2131	47 (29.4)	9.50	0.7556	23 (14.4)	0.2623	+0.71	0.1394

^a PCQ values greater than the 95^th percentile of the PCQ score distribution in non-exposed subjects (see ref [16])
^b Comparison of the PCQ score at baseline (t-test)
^c Comparison of the proportion of abnormal PCQ scores between T1 and T2 for each HRCT scan result (McNemar test)
^d ΔPCQ is defined as the PCQ at T2 - PCQ at T1 difference
^e Comparison between PCQ score at baseline and during follow-up for each HRCT scan result (paired t-test)

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