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Table 3 Course of PCQ scores and proportions of subjects with abnormal PCQ scorea between T1 and T2 according to the HRCT scan results (n = 832, univariate analyses)

From: CT scan screening is associated with increased distress among subjects of the APExS

    At T1    At T2     Variation  
CT scans N Abnormal PCQaN (%) Mean PCQ P valueb Abnormal PCQaN (%) Mean PCQ P valueb Acquiring
Abnormal PCQaN (%)
P value c Mean PCQd P valuee
Normal 213 44 (20.7) 8.02 Reference 57 (26.8) 9.28 Reference 31 (14.6) 0.0633 +1.26 0.0010
Isolated pulmonary Nodules (only) 79 15 (19.0) 8.99 0.2019 27 (34.2) 10.58 0.1497 17 (21.5) 0.0105 +1.59 0.0276
Pleural plaques (only) 113 21 (18.6) 7.77 0.6972 40 (35.4) 11.24 0.0078 24 (21.2) 0.0004 +3.47 <0.0001
Asbestosis (with or without pleural plaques) 67 13 (19.4) 8.40 0.9280 26 (38.8) 10.64 0.1303 18 (26.9) 0.0067 +2.24 0.0005
Other diseases (only) 151 28 (18.5) 8.38 0.5490 53 (35.1) 10.19 0.2037 32 (21.2) < 0.0001 +1.80 0.0002
Two or more of the above lesions 49 10 (20.4) 7.73 0.7504 21 (42.9) 10.86 0.1202 13 (26.5) 0.0045 +3.12 0.0002
Unknown results 160 40 (25.0) 8.79 0.2131 47 (29.4) 9.50 0.7556 23 (14.4) 0.2623 +0.71 0.1394
  1. a PCQ values greater than the 95th percentile of the PCQ score distribution in non-exposed subjects (see ref [16])
  2. b Comparison of the PCQ score at baseline (t-test)
  3. c Comparison of the proportion of abnormal PCQ scores between T1 and T2 for each HRCT scan result (McNemar test)
  4. d ΔPCQ is defined as the PCQ at T2 - PCQ at T1 difference
  5. e Comparison between PCQ score at baseline and during follow-up for each HRCT scan result (paired t-test)