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Table 2 Risk of incident cardiovascular disease in a cohort of adult population from Murcia (south-east Spain)

From: Cardiovascular risk estimated after 13 years of follow-up in a low-incidence Mediterranean region with high-prevalence of cardiovascular risk factors

 

Ischemic heart disease

Stroke

All events

 

Angina

AMI

All ischemic events

    
 

Py/cases

HR (95% CI)

Py/cases

HR (95% CI)

Py/cases

HR (95% CI)

Py/cases

HR (95% CI)

Py/cases

HR (95% CI)

Total cholesterol (mg/dl)

          

<200

15393/10

1

15404/8

1

15381/16

1

15454/19

1

15308/31

1

200-239

7154/8

1.14 (0.43-3.05)

7182/7

0.83 (0.29-2.39)

7138/12

0.97 (0.44-2.11)

7232/9

0.54 (0.23-1.28)

7104/18

0.71 (0.39-1.29)

≥240

3814/16

2.27 (0.91-5.68)

3813/22

2.85 (1.16-6.99)

3757/29

2.59 (1.30-5.14)

3913/9

0.79 (0.33-1.90)

7105/32

1.61 (0.92-2.81)

P for trend (categorical)

 

P = 0.075

 

P = 0.009

 

P = 0.005

 

P = 0.459

 

P = 0.119

     

P heterogneity by sex = 0.071

P heterogneity by sex = 0.500

P heterogneity by sex = 0.024

Triglycerides (mg/dl)

          

<150

20902/17

1

20947/14

1

20868/28

1

21041/26

1

20768/44

1

≥150

5459/17

1.64 (0.77-3.50)

5452/23

2.48 (1.17-5.27)

5408/29

1.64 (0.91-2.94)

5558/11

0.83 (0.39-1.79)

5369/37

1.52 (0.94-2.47)

     

P heterogneity by sex = 0.035

P heterogneity by sex = 0.003

P heterogneity by sex = 0.009

Blood pressure (mm Hg)

         

<140/90

19212/12

1

19151/9

1

19103/17

1

19258/13

1

19067/25

1

≥140/90

 

2.12 (0.95-4.71)

7248/28

3.68 (1.62-8.34)

7172/40

2.59 (1.39-4.84)

7341/24

1.92 (0.91-4.01)

7070/56

2.44 (1.46-4.07)

     

P heterogneity by sex = 0.040

P heterogneity by sex = 0.964

P heterogneity by sex = 0.101

Diabetes a

          

No

23620/23

1

23627/28

1

23553/40

1

23820/29

1

23449/61

1

Yes

2179/9

2.04 (0.95-4.71)

2199/9

1.77 (0.79-3.97)

2162/15

1.98 (1.02-3.83)

2216/7

1.45 (0.60-3.47)

2135/18

1.67 (0.96-2.92)

     

P heterogneity by sex = 0.004

P heterogneity by sex = 0.483

P heterogneity by sex = 0.010

Ever smoking

          

No

13623/15

1

13660/13

1

13597/21

1

13723/16

1

13526/32

1

Yes

2070/19

1.93 (0.78-4.74)

12739/24

1.94 (0.84-4.51)

12679/36

2.22 (1.10-4.46)

12875/21

3.88 (1.31-11.50)

12610/49

2.39 (1.31-4.38)

     

P heterogneity by sex = 0.010

P heterogneity by sex = 0.716

P heterogneity by sex = 0.030

BMI categories b

          

Normal weight

9328/4

1

9324/5

1

9317/7

1

9387/4

1

9306/10

1

Overweight

11221/18

1.07 (0.33-3.41)

11232/24

0.82 (0.29-2.33)

1176/33

1.06 (0.44-2.52)

11346/16

2.61 (0.72-9.42)

11114/43

1.29 (0.62-2.66)

Obese

5811/12

0.91 (0.26-3.18)

5843/8

0.38 (0.11-1.27)

5783/17

0.76 (0.29-1.99)

5866/17

2.56 (0.69-9.48)

5717/28

1.08 (0.50-2.34)

P for trend (categorical)

 

P = 0.801

 

P = 0.065

 

P = 0.455

 

P = 0.216

 

P = 0.950

     

-c

-c

-c

  1. AMI: Acute myocardial infarction; Py: Person-years. HR: Hazard ratio. CI: confidence interval.
  2. Cox models adjusted by all variables in the table, plus educational level and physical activity of moderate and high intensity, and stratified by sex and age.
  3. aDefined as a self-reported diagnosis of diabetes or prescription of insulin or oral anti-diabetic medication.
  4. bNormal weight: Body mass index (BMI) <24.9 kg/m2; overweight: 25 ≤ BMI < 29.9 kg/m2; obese: BMI ≥30 kg/m2.
  5. cHeterogeneity by sex cannot be assessed because the lack of cases in the reference category for women prevents fitting a regression model.
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BMC Public Health

ISSN: 1471-2458

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